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Antimicrobial Agents and Chemotherapy, March 2000, p. 783-786, Vol. 44, No. 3
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Antiviral Activity of 2'-Deoxy-3'-Oxa-4'-Thiocytidine (BCH-10652) against Lamivudine-Resistant Human Immunodeficiency Virus Type 1 in SCID-hu Thy/Liv Mice

Cheryl A. Stoddart,^1,* Mary E. Moreno,¹ Valerie D. Linquist-Stepps,¹ Christopher Bare,¹ Mark R. Bogan,¹ Alberto Gobbi,^1, Robert W. Buckheit Jr.,² Jean Bedard,³ Robert F. Rando,³ and Joseph M. McCune^1,4

Antiviral Drug Research Division, Gladstone Institute of Virology and Immunology,¹ and Departments of Medicine and Microbiology and Immunology,⁴ University of California, San Francisco, California; Southern Research Institute, Frederick, Maryland 21701-4756,² and Department of Virology, BioChem Pharma Inc., Laval, Quebec, Canada H7V 4A7³

Received 21 July 1999/Returned for modification 22 October 1999/Accepted 29 November 1999

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