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Antimicrobial Agents and Chemotherapy, April 2000, p. 1112-1113, Vol. 44, No. 4
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

In Vitro Activity of ABT 773, a New Ketolide Antibiotic, against Chlamydia pneumoniae

Sebastian Strigl, Patricia M. Roblin, Tamara Reznik, and Margaret R. Hammerschlag*

Division of Infectious Diseases, Department of Pediatrics, State University of New York Health Science Center at Brooklyn, Brooklyn, New York 11203-2098

Received 11 October 1999/Returned for modification 23 December 1999/Accepted 15 January 2000

The in vitro activities of ABT 773, telithromycin (HMR 3647), azithromycin, clarithromycin, erythromycin, and levofloxacin were tested against 20 strains of Chlamydia pneumoniae. The MIC at which 90% of the isolates were inhibited and the minimal bactericidal concentration at which 90% of the isolates were killed by ABT 773 were 0.015 µg/ml (range, 0.008 to 0.015 µg/ml). ABT 773 was the most active antibiotic tested in this study.

* Corresponding author. Mailing address: Department of Pediatrics, Box 49, SUNY Health Science Center at Brooklyn, 450 Clarkson Ave., Brooklyn, NY 11203-2098. Phone: (718) 245-4075. Fax: (718) 245-2118. E-mail: mhammerschlag{at}pol.net.

Antimicrobial Agents and Chemotherapy, April 2000, p. 1112-1113, Vol. 44, No. 4
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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