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Antimicrobial Agents and Chemotherapy, May 2000, p. 1342-1345, Vol. 44, No. 5
Departments of Laboratory Medicine and
Internal Medicine, National Taiwan University Hospital,
Taipei,1 Veterans General Hospital,
Kaohsiung,2 Veterans General Hospital,
Taichung,3 Chang Gung Memorial
Hospital, LinKou,4 and National
Cheng-Kung University Hospital, Tainan,5 Taiwan
Received 6 August 1999/Returned for modification 7 December
1999/Accepted 24 January 2000
A susceptibility surveillance study of 276 isolates of
Streptococcus pneumoniae, 301 of Haemophilus
influenzae, and 110 of Moraxella catarrhalis was
carried out from November 1998 to May 1999 in Taiwan. High rates of
nonsusceptibility to penicillin (76%), extended-spectrum
cephalosporins (56%), azithromycin (94%), clarithromycin (95%), and
trimethoprim-sulfamethoxazole (TMP-SMX) (65%) for S. pneumoniae isolates and high rates of nonsusceptibility to
amoxicillin (58%) and TMP-SMX (52%) for H. influenzae
isolates were found. Higher percentages of S. pneumoniae
isolates nonsusceptible to aminopenicillins, extended-spectrum
cephalosporins, macrolides, and TMP-SMX were observed among
penicillin-intermediate and -resistant isolates. All quinolones tested
were active in vitro against these three organisms.
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
Multicenter Surveillance of Antimicrobial
Resistance of Streptococcus pneumoniae, Haemophilus
influenzae, and Moraxella catarrhalis in Taiwan
during the 1998-1999 Respiratory Season
*
Corresponding author. Mailing address: Department of
Laboratory Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Rd., Taipei, Taiwan. Phone: 886-2-23562149. Fax:
886-2-23224263. E-mail: luhkt{at}ha.mc.ntu.edu.tw.
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