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Antimicrobial Agents and Chemotherapy, May 2000, p. 1342-1345, Vol. 44, No. 5
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Multicenter Surveillance of Antimicrobial Resistance of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in Taiwan during the 1998-1999 Respiratory Season

Po-Ren Hsueh,1 Yung-Ching Liu,2 Jainn-Ming Shyr,3 Tsu-Lan Wu,4 Jing-Jou Yan,5 Jiunn-Jong Wu,5 Hsieh-Shong Leu,4 Yin-Ching Chuang,5 Yeu-Jen Lau,3 and Kwen-Tay Luh1,*

Departments of Laboratory Medicine and Internal Medicine, National Taiwan University Hospital, Taipei,1 Veterans General Hospital, Kaohsiung,2 Veterans General Hospital, Taichung,3 Chang Gung Memorial Hospital, LinKou,4 and National Cheng-Kung University Hospital, Tainan,5 Taiwan

Received 6 August 1999/Returned for modification 7 December 1999/Accepted 24 January 2000

A susceptibility surveillance study of 276 isolates of Streptococcus pneumoniae, 301 of Haemophilus influenzae, and 110 of Moraxella catarrhalis was carried out from November 1998 to May 1999 in Taiwan. High rates of nonsusceptibility to penicillin (76%), extended-spectrum cephalosporins (56%), azithromycin (94%), clarithromycin (95%), and trimethoprim-sulfamethoxazole (TMP-SMX) (65%) for S. pneumoniae isolates and high rates of nonsusceptibility to amoxicillin (58%) and TMP-SMX (52%) for H. influenzae isolates were found. Higher percentages of S. pneumoniae isolates nonsusceptible to aminopenicillins, extended-spectrum cephalosporins, macrolides, and TMP-SMX were observed among penicillin-intermediate and -resistant isolates. All quinolones tested were active in vitro against these three organisms.


* Corresponding author. Mailing address: Department of Laboratory Medicine, National Taiwan University Hospital, No. 7 Chung-Shan South Rd., Taipei, Taiwan. Phone: 886-2-23562149. Fax: 886-2-23224263. E-mail: luhkt{at}ha.mc.ntu.edu.tw.


Antimicrobial Agents and Chemotherapy, May 2000, p. 1342-1345, Vol. 44, No. 5
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.



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