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Antimicrobial Agents and Chemotherapy, May 2000, p. 1365-1366, Vol. 44, No. 5
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Spectinomycin Resistance in Neisseria spp. Due to Mutations in 16S rRNA

Marc Galimand,* Guy Gerbaud, and Patrice Courvalin

Unité des Agents Antibactériens, Institut Pasteur, 75724 Paris Cedex 15, France

Received 2 August 1999/Returned for modification 26 November 1999/Accepted 24 January 2000

Spectinomycin resistance in clinical isolates of Neisseria meningitidis and Neisseria gonorrhoeae was found to be due to mutations G1064C and C1192U (Escherichia coli numbering) in 16S rRNA genes, respectively.

* Corresponding author. Mailing address: Unité des Agents Antibactériens, Institut Pasteur, 25, rue du Docteur Roux, 75724 Paris Cedex 15, France. Phone: (33) (1) 45 68 83 18. Fax: (33) (1) 45 68 83 19. E-mail: galimand{at}pasteur.fr.

Antimicrobial Agents and Chemotherapy, May 2000, p. 1365-1366, Vol. 44, No. 5
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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