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Antimicrobial Agents and Chemotherapy, June 2000, p. 1705-1707, Vol. 44, No. 6
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Antibiotic Susceptibility Patterns of Neisseria meningitidis Isolates from Patients and Asymptomatic Carriers

L. Arreaza, L. de la Fuente, and J. A. Vázquez*

Laboratorio de Referencia de Meningococos. Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain

Received 4 August 1999/Returned for modification 1 December 1999/Accepted 26 February 2000

The activities of seven antimicrobial agents used for treatment and prophylaxis of meningococcal disease was investigated against 901 Neisseria meningitidis isolates, 112 of which were recovered from patients and 789 of which were recovered from asymptomatic carriers. The proportions of isolates with decreased susceptibility to penicillin were 55.3 and 39.0%, respectively. Penicillin- and ampicillin-intermediate strains were more common among serogroup C meningococci than among non-serogroup C meningococci from both patients and carriers.

* Corresponding author. Mailing address: Servicio de Bacteriología, Laboratorio de Referencia de Meningococos, Centro Nacional de Microbiología, Instituto de Salud Carlos III. 28220 Majadahonda, Madrid, Spain. Phone: 34-1-5097901. Fax: 34-1-5097966. E-mail: jvazquez{at}isciii.es.

Antimicrobial Agents and Chemotherapy, June 2000, p. 1705-1707, Vol. 44, No. 6
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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