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Antimicrobial Agents and Chemotherapy, July 2000, p. 1997-2000, Vol. 44, No. 7
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.

Effects of Amphotericin B and Three Azole Derivatives on the Lipids of Yeast Cells of Paracoccidioides brasiliensis

Rosane Christine Hahn and Júnia Soares Hamdan*

Department of Microbiology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

Received 6 July 1999/Returned for modification 15 January 2000/Accepted 18 April 2000

Yeast cells of five different strains of Paracoccidioides brasiliensis were obtained for partial analysis of lipid composition, and sterol content was determined quantitatively and qualitatively. The determinations were conducted with cells cultured in the presence and absence of amphotericin B and azole derivatives at levels below the MIC.

* Corresponding author. Mailing address: Dra. Júnia Soares Hamdan, Departamento de Microbiologia, ICB/UFMG, Av. Antônio Carlos, 6627, 31270-901-Belo Horizonte, Minas Gerais, Brazil. Phone: 55 31 499-2758. Fax: 55 31 499-2730. E-mail: handan{at}icb.ufmg.br.

Antimicrobial Agents and Chemotherapy, July 2000, p. 1997-2000, Vol. 44, No. 7
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.


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