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Antimicrobial Agents and Chemotherapy, September 2000, p. 2530-2533, Vol. 44, No. 9
Institut für Tierzucht und
Tierverhalten der Bundesforschungsanstalt für Landwirtschaft
Braunschweig (FAL), 29223 Celle,1 and
Institut für Medizinische Mikrobiologie, Infektions- und
Seuchenmedizin, Tierärztliche Fakultät der
Ludwig-Maximilians-Universität München, 80539 Munich,2 Germany
Received 18 January 2000/Returned for modification 23 March
2000/Accepted 14 June 2000
The 16.5-kbp plasmid pSCFS1 from Staphylococcus sciuri
mediated combined resistance to chloramphenicol and florfenicol. The gene responsible for this resistance property, cfr, was
cloned and sequenced. The amino acid sequence of the Cfr protein
revealed no homology to known acetyltransferases or efflux proteins
involved in chloramphenicol and/or florfenicol resistance or to other
proteins whose functions are known.
0066-4804/00/$04.00+0
Copyright © 2000, American Society for Microbiology. All rights reserved.
Identification of a Plasmid-Borne
Chloramphenicol-Florfenicol Resistance Gene in
Staphylococcus sciuri
*
Corresponding author. Mailing address: Institut
für Tierzucht und Tierverhalten der Bundesforschungsanstalt
für Landwirtschaft Braunschweig (FAL), Dörnbergstr. 25-27, 29223 Celle, Germany. Phone: 49-5141-384673 or -384675. Fax:
49-5141-381849. E-mail: schwarz{at}ktf.fal.de.
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