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Antimicrobial Agents and Chemotherapy, January 2001, p. 301-302, Vol. 45, No. 1
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.1.301-302.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Bacteriostatic and Bactericidal Activities of Moxifloxacin against Coxiella burnetii

Jean-Marc Rolain, Max Maurin, and Didier Raoult*

Unité des Rickettsies CNRS UPRES-A 6020, Faculté de Médecine, Université de la Méditerranée, 13385 Marseille Cedex 05, France

Received 6 March 2000/Returned for modification 21 August 2000/Accepted 29 September 2000

The in vitro activity of moxifloxacin against Coxiella burnetii was compared to those of pefloxacin, ofloxacin, and doxycycline. MICs of moxifloxacin ranged from 0.5 to 1 µg/ml for the Nine Mile, Priscilla, and Q212 strains. Moxifloxacin was not bactericidal against C. burnetii at 4 µg/ml.


* Corresponding author. Mailing address: Unité des Rickettsies, Faculté de Médecine, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 5, France. Phone: 33.04.91.32.43.75. Fax: 33.04.91.38.77.72. E-mail: Didier.Raoult{at}medecine.univ-mrs.fr.


Antimicrobial Agents and Chemotherapy, January 2001, p. 301-302, Vol. 45, No. 1
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.1.301-302.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.



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