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Antimicrobial Agents and Chemotherapy, October 2001, p. 2943-2946, Vol. 45, No. 10
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.10.2943-2946.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Transfer of Tn916-Like Elements in Microcosm Dental Plaques

Adam P. Roberts,1,* Grace Cheah,1 Derren Ready,2 Jonathan Pratten,1 Michael Wilson,1 and Peter Mullany1

Department of Microbiology, Eastman Dental Institute for Oral Health Care Sciences,1 and Eastman Dental Hospital,2 University College London, London WC1X 8LD, United Kingdom

Received 22 January 2001/Returned for modification 28 March 2001/Accepted 16 July 2001

Microcosm dental plaques were grown from an inoculum of human saliva in a constant-depth film fermentor. The inoculum contained four tetracycline-resistant streptococcal species, each of which contained a Tn916-like element. This element was shown to transfer to other streptococci both in filter-mating experiments and within the biofilms in the fermentor.


* Corresponding author. Mailing address: Department of Microbiology, Eastman Dental Institute for Oral Health Care Sciences, University College London, 256 Gray's Inn Rd., London WC1X 8LD, United Kingdom. Phone: 44 (0) 20 7915 1050. Fax: 44 (0) 20 7915 1127. E-mail: aroberts{at}eastman.ucl.ac.uk.


Antimicrobial Agents and Chemotherapy, October 2001, p. 2943-2946, Vol. 45, No. 10
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.10.2943-2946.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.



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Copyright © 2001 by the American Society for Microbiology. All rights reserved.