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Antimicrobial Agents and Chemotherapy, December 2001, p. 3623-3624, Vol. 45, No. 12
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.12.3623-3624.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Antimicrobial Susceptibilities of Group B Streptococci Isolated from Patients with Invasive Disease: 10-Year Perspective

David R. Murdoch* and L. Barth Reller

Clinical Microbiology Laboratory, Duke University Medical Center, Durham, North Carolina 27710

Received 1 June 2001/Returned for modification 3 July 2001/Accepted 5 September 2001

Antimicrobial susceptibility testing of 192 group B streptococcal isolates from patients with invasive disease demonstrated that 31 (16%) were resistant to erythromycin and 17 (9%) were resistant to clindamycin. One isolate demonstrated high-level resistance to streptomycin, but none was highly resistant to gentamicin. Erythromycin and clindamycin are no longer reliable empirical alternatives to penicillin for the treatment and prevention of group B streptococcal infections.

* Corresponding author. Present address: Microbiology Unit, Canterbury Health Laboratories, P.O. Box 151, Christchurch, New Zealand. Phone: 64 3 364 0347. Fax: 64 3 364 0238. E-mail: david.murdoch{at}cdhb.govt.nz.

Antimicrobial Agents and Chemotherapy, December 2001, p. 3623-3624, Vol. 45, No. 12
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.12.3623-3624.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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