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Antimicrobial Agents and Chemotherapy, December 2001, p. 3647-3650, Vol. 45, No. 12
Division of Animal and Food Microbiology,
Office of Research, Center for Veterinary Medicine, U.S. Food and
Drug Administration, Laurel, Maryland 207081;
Department of Nutrition and Food Science, University of
Maryland, College Park, Maryland 207422;
Department of Avian Medicine, University of Georgia,
Athens, Georgia, 306023; and Department
of Veterinary Diagnostic and Production Animal Medicine, Iowa State
University, Ames, Iowa 500114
Received 7 March 2001/Returned for modification 17 August
2001/Accepted 20 September 2001
Twenty-one Salmonella and 54 Escherichia
coli isolates, recovered from food animals and retail ground
meats, that exhibited decreased susceptibilities to ceftiofur and
ceftriaxone were shown to possess a blaCMY
gene. The blaCMY-4 gene
was identified in an E. coli isolate recovered
from retail chicken and was further shown to be responsible for
resistance to cephalothin, ampicillin, and amoxicillin-clavulanic acid
and elevated MICs of ceftriaxone, cefoxitin, and ceftiofur.
0066-4804/01/$04.00+0 DOI: 10.1128/AAC.45.12.3647-3650.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.
Identification and Expression of Cephamycinase
blaCMY Genes in Escherichia coli
and Salmonella Isolates from Food Animals and Ground
Meat
*
Corresponding author. Mailing address: Office of
Research, U.S. FDA/CVM, 8401 Muirkirk Rd., Laurel, MD 20708. Phone:
(301) 827-8139. Fax: (301) 827-8127. E-mail:
szhao{at}cvm.fda.gov.
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