This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by de Champs, C.
Right arrow Articles by Sirot, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by de Champs, C.
Right arrow Articles by Sirot, J.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, April 2001, p. 1278-1280, Vol. 45, No. 4
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.4.1278-1280.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

New TEM Variant (TEM-92) Produced by Proteus mirabilis and Providencia stuartii Isolates

Christophe de Champs,1,* Claire Monne,2 Richard Bonnet,1 Wladimir Sougakoff,2 Danielle Sirot,1 Catherine Chanal,1 and Jacques Sirot1

Laboratoire de Bactériologie, Faculté de Médecine, 63001 Clermont-Ferrand Cedex,1 and Laboratoire de Bactériologie-Hygiène, Faculté de Médecine Pitié-Salpêtrière, 75634 Paris Cedex 13,2 France

Received 27 July 2000/Returned for modification 28 October 2000/Accepted 1 January 2001

The sequences of the blaTEM genes encoding TEM-92 in Proteus mirabilis and Providencia stuartii isolates were determined and were found to be identical. Except for positions 218 (Lys-6) and 512 (Lys-104), the nucleotide sequence of blaTEM-92 was identical to that of blaTEM-20, including the sequence of the promoter region harboring a 135-bp deletion combined with a G-162right-arrowT substitution. The deduced amino acid sequence of TEM-92 differed from that of TEM-52 by the presence of a substitution (Gln-6right-arrowLys) in the peptide signal.

* Corresponding author. Mailing address: Laboratoire de Bactériologie, Faculté de Médecine, 28, place Henri Dunant, 63001 Clermont-Ferrand Cedex, France. Phone: 33.(0)4.73.60.80.18. Fax: 33.(0)4.73.27.74.94. E-mail: Christophe.DECHAMPS{at}u-clermont1.fr.

Antimicrobial Agents and Chemotherapy, April 2001, p. 1278-1280, Vol. 45, No. 4
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.4.1278-1280.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Goldsmith, M., Tawfik, D. S. (2009). Potential role of phenotypic mutations in the evolution of protein expression and stability. Proc. Natl. Acad. Sci. USA 106: 6197-6202 [Abstract] [Full Text]  
  • Lachmayr, K. L., Kerkhof, L. J., DiRienzo, A. G., Cavanaugh, C. M., Ford, T. E. (2009). Quantifying Nonspecific TEM {beta}-Lactamase (blaTEM) Genes in a Wastewater Stream. Appl. Environ. Microbiol. 75: 203-211 [Abstract] [Full Text]  
  • Savini, V., Catavitello, C., Talia, M., Di Berardino, F., Manna, A., Balbinot, A., Febbo, F., Carlino, D., Fioritoni, F., Di Bonaventura, G., D'Antonio, D. (2008). Ulcer Infection by ES{beta}L-Producing Proteus mirabilis: A Case Report. INT J LOW EXTREM WOUNDS 7: 99-101 [Abstract]  
  • Endimiani, A., Luzzaro, F., Migliavacca, R., Mantengoli, E., Hujer, A. M., Hujer, K. M., Pagani, L., Bonomo, R. A., Rossolini, G. M., Toniolo, A. (2007). Spread in an Italian Hospital of a Clonal Acinetobacter baumannii Strain Producing the TEM-92 Extended-Spectrum {beta}-Lactamase. Antimicrob. Agents Chemother. 51: 2211-2214 [Abstract] [Full Text]  
  • Tristram, S. G., Hawes, R., Souprounov, J. (2005). Variation in selected regions of blaTEM genes and promoters in Haemophilus influenzae. J Antimicrob Chemother 56: 481-484 [Abstract] [Full Text]  
  • Ho, P. L., Ho, A. Y. M., Chow, K. H., Wong, R. C. W., Duan, R. S., Ho, W. L., Mak, G. C., Tsang, K. W., Yam, W. C., Yuen, K. Y. (2005). Occurrence and molecular analysis of extended-spectrum {beta}-lactamase-producing Proteus mirabilis in Hong Kong, 1999-2002. J Antimicrob Chemother 55: 840-845 [Abstract] [Full Text]  
  • Perilli, M., Segatore, B., De Massis, M. R., Pagani, L., Luzzaro, F., Rossolini, G. M., Amicosante, G. (2002). Biochemical Characterization of TEM-92 Extended-Spectrum {beta}-Lactamase, a Protein Differing from TEM-52 in the Signal Peptide. Antimicrob. Agents Chemother. 46: 3981-3983 [Abstract] [Full Text]  
  • Pagani, L., Migliavacca, R., Pallecchi, L., Matti, C., Giacobone, E., Amicosante, G., Romero, E., Rossolini, G. M. (2002). Emerging Extended-Spectrum {beta}-Lactamases in Proteus mirabilis. J. Clin. Microbiol. 40: 1549-1552 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»