Antimicrobial Agents and Chemotherapy, April 2001, p. 1305-1308, Vol. 45, No. 4
0066-4804/01/$04.00+0 DOI: 10.1128/AAC.45.4.1305-1308.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.
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Área de Microbiología, Departamento de Biología Funcional, Universidad de Oviedo, 33006 Oviedo, Principado de Asturias, Spain
Received 7 August 2000/Returned for modification 24 October 2000/Accepted 10 January 2001
A multidrug-resistant Salmonella enterica serotype
[4,5,12:i:
] clone carried a class 1 integron harboring
dfrA12 and aadA2 gene cassettes and
blaTEM-1, aac(3)-IV,
cmlA1, and tetA genes located in large plasmids
of about 140 kb (carrying spv) or 120 kb (lacking
spv). Several segregants, lacking multidrug resistance, contained a plasmid smaller than the parental one and no longer hybridized with probes for the lost resistances. The genes mediating resistance to ampicillin, chloramphenicol, and tetracycline in the
[4,5,12:i:
] clone are different from those found in the
pentadrug-resistant serotype Typhimurium DT104 clone.
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