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Antimicrobial Agents and Chemotherapy, June 2001, p. 1896-1899, Vol. 45, No. 6
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.6.1896-1899.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Comparative In Vitro Activities of Gemifloxacin, Other Quinolones, and Nonquinolone Antimicrobials against Obligately Anaerobic Bacteria

Niels Kleinkauf,* Grit Ackermann, Reiner Schaumann, and Arne C. Rodloff

Institute for Medical Microbiology and Epidemiology of Infectious Diseases, University of Leipzig, Leipzig, Germany

Received 27 November 2000/Returned for modification 17 January 2001/Accepted 6 March 2001

The in vitro activity of gemifloxacin was compared to that of other quinolone and nonquinolone antimicrobials against 204 anaerobes by the agar dilution technique. The data indicate that gemifloxacin has a rather selective anaerobic activity. Most Peptostreptococcus, Porphyromonas, and Fusobacterium species are susceptible, while gemifloxacin's activity against other gram-negative anaerobes appears to be variable.

* Corresponding author. Mailing address: University of Leipzig, Institute for Medical Microbiology and Epidemiology of Infectious Diseases, Liebigstr. 24, D-04103 Leipzig, Germany. Phone: 49 (341) 9715200. Fax: 49 (341) 9715209. E-mail: klen{at}medizin.uni-leipzig.de.

Antimicrobial Agents and Chemotherapy, June 2001, p. 1896-1899, Vol. 45, No. 6
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.6.1896-1899.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


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