This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Cloeckaert, A.
Right arrow Articles by Chaslus-Dancla, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cloeckaert, A.
Right arrow Articles by Chaslus-Dancla, E.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, August 2001, p. 2381-2382, Vol. 45, No. 8
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.8.2381-2382.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.

Nonenzymatic Chloramphenicol Resistance Mediated by IncC Plasmid R55 Is Encoded by a floR Gene Variant

Axel Cloeckaert,* Sylvie Baucheron, and Elisabeth Chaslus-Dancla

Station de Pathologie Aviaire et Parasitologie, Institut National de la Recherche Agronomique, 37380 Nouzilly, France

Received 23 January 2001/Returned for modification 6 April 2001/Accepted 3 May 2001

The IncC plasmid R55, initially described in the 1970s and isolated from Klebsiella pneumoniae, confers nonenzymatic chloramphenicol resistance. The gene coding for this resistance was cloned and sequenced and shows 95 to 97% nucleotide identity with the recently reported floR gene from Salmonella enterica serovar Typhimurium DT104 and from Escherichia coli animal isolates, respectively, conferring cross-resistance to florfenicol.

* Corresponding author. Mailing address: Station de Pathologie Aviaire et Parasitologie, Institut National de la Recherche Agronomique, 37380 Nouzilly, France. Phone: (33) 2 47427750. Fax: (33) 2 47427774. E-mail: cloeckae{at}tours.inra.fr.

Antimicrobial Agents and Chemotherapy, August 2001, p. 2381-2382, Vol. 45, No. 8
0066-4804/01/$04.00+0   DOI: 10.1128/AAC.45.8.2381-2382.2001
Copyright © 2001, American Society for Microbiology. All rights reserved.


This article has been cited by other articles:

  • Levings, R. S., Djordjevic, S. P., Hall, R. M. (2008). SGI2, a Relative of Salmonella Genomic Island SGI1 with an Independent Origin. Antimicrob. Agents Chemother. 52: 2529-2537 [Abstract] [Full Text]  
  • Kehrenberg, C., Schwarz, S. (2006). Distribution of Florfenicol Resistance Genes fexA and cfr among Chloramphenicol-Resistant Staphylococcus Isolates.. Antimicrob. Agents Chemother. 50: 1156-1163 [Abstract] [Full Text]  
  • Wu, B., Xia, C., Du, X., Cao, X., Shen, J. (2006). Influence of Anti-FloR Antibody on Florfenicol Accumulation in Florfenicol-Resistant Escherichia coli and Enzyme-Linked Immunosorbent Assay for Detection of Florfenicol-Resistant E. coli Isolates. J. Clin. Microbiol. 44: 378-382 [Abstract] [Full Text]  
  • Doublet, B., Schwarz, S., Kehrenberg, C., Cloeckaert, A. (2005). Florfenicol Resistance Gene floR Is Part of a Novel Transposon. Antimicrob. Agents Chemother. 49: 2106-2108 [Abstract] [Full Text]  
  • Blickwede, M., Schwarz, S. (2004). Molecular analysis of florfenicol-resistant Escherichia coli isolates from pigs. J Antimicrob Chemother 53: 58-64 [Abstract] [Full Text]  
  • Gayet, S., Chollet, R., Molle, G., Pages, J.-M., Chevalier, J. (2003). Modification of Outer Membrane Protein Profile and Evidence Suggesting an Active Drug Pump in Enterobacter aerogenes Clinical Strains. Antimicrob. Agents Chemother. 47: 1555-1559 [Abstract] [Full Text]  
  • Meunier, D., Baucheron, S., Chaslus-Dancla, E., Martel, J.-L., Cloeckaert, A. (2003). Florfenicol resistance in Salmonella enterica serovar Newport mediated by a plasmid related to R55 from Klebsiella pneumoniae. J Antimicrob Chemother 51: 1007-1009 [Abstract] [Full Text]  
  • Sanchez, S., McCrackin Stevenson, M. A., Hudson, C. R., Maier, M., Buffington, T., Dam, Q., Maurer, J. J. (2002). Characterization of Multidrug-Resistant Escherichia coli Isolates Associated with Nosocomial Infections in Dogs. J. Clin. Microbiol. 40: 3586-3595 [Abstract] [Full Text]  
  • Boyd, D., Cloeckaert, A., Chaslus-Dancla, E., Mulvey, M. R. (2002). Characterization of Variant Salmonella Genomic Island 1 Multidrug Resistance Regions from Serovars Typhimurium DT104 and Agona. Antimicrob. Agents Chemother. 46: 1714-1722 [Abstract] [Full Text]  
  • Bischoff, K. M., White, D. G., McDermott, P. F., Zhao, S., Gaines, S., Maurer, J. J., Nisbet, D. J. (2002). Characterization of Chloramphenicol Resistance in Beta-Hemolytic Escherichia coli Associated with Diarrhea in Neonatal Swine. J. Clin. Microbiol. 40: 389-394 [Abstract] [Full Text]  
  • Doublet, B., Schwarz, S., Nu{beta}beck, E., Baucheron, S., Martel, J.-L., Chaslus-Dancla, E., Cloeckaert, A. (2002). Molecular analysis of chromosomally florfenicol-resistant Escherichia coli isolates from France and Germany. J Antimicrob Chemother 49: 49-54 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»