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Antimicrobial Agents and Chemotherapy, January 2002, p. 239-241, Vol. 46, No. 1
0066-4804/01/$04.00+0     DOI: 10.1128/AAC.46.2.239-241.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Multicenter Study on Spreading of the tet(M) Gene in Tetracycline-Resistant Streptococcus Group G and C Isolates in Argentina

P. E. Jeric,1* H. Lopardo,2 P. Vidal,2 S. Arduino,3 A. Fernandez,4 B. E. Orman,1 D. O. Sordelli,1 and D. Centrón1

Departamento de Microbiología, Facultad de Medicina, Universidad de Buenos Aires,1 Hospital de Pediatría, Dr. Juan P. Garrahan,2 Instituto Alexander Fleming,3 Hospital Dr. Alejandro Posadas, Buenos Aires, Argentina4

Received 28 June 2001/ Returned for modification 15 August 2001/ Accepted 26 September 2001

A prospective multicenter study on invasive infections caused by beta-hemolytic streptococci was performed over 6 months and involved 42 centers from 16 cities in Argentina. Among 33 isolates recovered, 9 group G Streptococcus isolates (39.1%) and 2 group C Streptococcus isolates (20%) exhibited resistance to tetracycline and harbored the tet(M) gene. Genealogical analysis revealed that tetracycline resistance has a polyclonal origin in Argentina.


* Corresponding author. Mailing address: Departamento de Microbiología, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2155, piso 12 (1121), Buenos Aires, Argentina. Phone: (5411) 4963-6669. Fax: (5411) 4508-3705. E-mail: pvjeric{at}ciudad.com.ar.


Antimicrobial Agents and Chemotherapy, January 2002, p. 239-241, Vol. 46, No. 1
0066-4804/01/$04.00+0     DOI: 10.1128/AAC.46.2.239-241.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.




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