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Antimicrobial Agents and Chemotherapy, November 2002, p. 3621-3623, Vol. 46, No. 11
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.11.3621-3623.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Staphylococcus sciuri Gene erm(33), Encoding Inducible Resistance to Macrolides, Lincosamides, and Streptogramin B Antibiotics, Is a Product of Recombination between erm(C) and erm(A)

Stefan Schwarz,1* Corinna Kehrenberg,1 and Kayode K. Ojo1,2

Institut für Tierzucht, Bundesforschungsanstalt für Landwirtschaft (FAL), 31535 Neustadt-Mariensee, Germany,1 Department of Pharmaceutical Microbiology and Clinical Pharmacy, College of Medicine, University of Ibadan, Nigeria2

Received 28 March 2002/ Returned for modification 10 May 2002/ Accepted 25 July 2002

A gene which mediates inducible resistance to macrolides, lincosamides, and streptogramin B antibiotics, designated erm(33), was detected on the Staphylococcus sciuri plasmid pSCFS1. Analysis of the erm(33) reading frame suggested that this gene was the product of a recombination between an erm(C) gene and an erm(A) gene. Such a recombination event is a novel observation for erm genes.

* Corresponding author. Mailing address: Institut für Tierzucht der Bundesforschungsanstalt für Landwirtschaft (FAL), Höltystr. 10, 31535 Neustadt-Mariensee, Germany. Phone: 49-5034-871-241. Fax: 49-5034-871-246. E-mail: stefan.schwarz{at}fal.de.

Antimicrobial Agents and Chemotherapy, November 2002, p. 3621-3623, Vol. 46, No. 11
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.11.3621-3623.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Kehrenberg, C., Ojo, K. K., Schwarz, S. (2004). Nucleotide sequence and organization of the multiresistance plasmid pSCFS1 from Staphylococcus sciuri. J Antimicrob Chemother 54: 936-939 [Abstract] [Full Text]  
  • Kehrenberg, C., Schwarz, S. (2004). fexA, a Novel Staphylococcus lentus Gene Encoding Resistance to Florfenicol and Chloramphenicol. Antimicrob. Agents Chemother. 48: 615-618 [Abstract] [Full Text]  


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