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Antimicrobial Agents and Chemotherapy, November 2002, p. 3624-3626, Vol. 46, No. 11
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.11.3624-3626.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Clinical Strain of Pseudomonas aeruginosa Carrying a bla_TEM-21 Gene Located on a Chromosomal Interrupted TnA Type Transposon

Laboratoire de Microbiologie, Faculté de Pharmacie, Université de Bordeaux 2, Bordeaux,¹ Laboratoire d'Analyses Médicales, Villenave d'Ornon, France²

Received 23 January 2002/ Returned for modification 6 May 2002/ Accepted 9 August 2002

A clinical isolate of Pseudomonas aeruginosa was found to produce a clavulanic acid-inhibited extended-spectrum ß-lactamase with a pI of 6.4. PCR, cloning, and sequencing experiments showed that the corresponding bla_TEM-21 gene was part of a chromosomally located Tn801 transposon disrupted by an IS6100 element and adjacent to an aac(3)-II gene.

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