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Antimicrobial Agents and Chemotherapy, December 2002, p. 3843-3845, Vol. 46, No. 12
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.12.3843-3845.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Antimicrobial Susceptibilities of Diverse Bacillus anthracis Isolates

Pamala R. Coker,1* Kimothy L. Smith,2 and Martin E. Hugh-Jones1

Department of Pathobiological Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, Louisiana 70803,1 Lawrence Livermore National Laboratory, Livermore, California 945512

Received 21 March 2002/ Returned for modification 29 July 2002/ Accepted 5 September 2002

A test of 25 genetically diverse isolates of Bacillus anthracis was conducted to determine their susceptibility to seven clinically relevant antimicrobial agents. Etest strips (AB BIODISK, Solna, Sweden) were used to measure the MICs for the isolates. Using the National Committee for Clinical Laboratory Standards MIC breakpoints for staphylococci, three isolates were found to be resistant to penicillin and five were found to be resistant to cefuroxime. The penicillin-resistant isolates were negative for ß-lactamase production. Continued surveillance of B. anthracis field isolates is recommended to monitor antimicrobial susceptibility.

* Corresponding author. Mailing address: Department of Pathobiological Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, LA 70803. Phone: (225) 578-9659. Fax: (225) 578-7117. E-mail: Banthracis{at}vetmed.lsu.edu.

Antimicrobial Agents and Chemotherapy, December 2002, p. 3843-3845, Vol. 46, No. 12
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.12.3843-3845.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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