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Antimicrobial Agents and Chemotherapy, April 2002, p. 1147-1152, Vol. 46, No. 4
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.4.1147-1152.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Novel Type of Staphylococcal Cassette Chromosome mec Identified in Community-Acquired Methicillin-Resistant Staphylococcus aureus Strains

Xiao Xue Ma,1 Teruyo Ito,1 Chuntima Tiensasitorn,1 Mantana Jamklang,1 Piriyaporn Chongtrakool,1 Susan Boyle-Vavra,2 Robert S. Daum,2 and Keiichi Hiramatsu1*

Department of Bacteriology, Juntendo University, Tokyo, Japan,1 Department of Pediatrics, University of Chicago Children's Hospital, Chicago, Illinois2

Received 25 July 2001/ Returned for modification 10 October 2001/ Accepted 28 November 2001

We identified a new type of staphylococcal cassette chromosome mec (SCCmec) from two community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains. The novel element, designated type IV SCCmec, had a unique combination of the class B mec gene complex and the type 2 ccr gene complex and was much smaller in size (21 to 24 kb) than previously identified SCCmec elements of hospital-acquired MRSA. Consistent with the strains' susceptibilities to various non-ß-lactam antibiotics, the type IV SCCmec was devoid of any antibiotic resistance genes other than the mecA gene.

* Corresponding author. Mailing address: Department of Bacteriology, Juntendo University, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan 113-8421. Phone: 81-3-5802-1040. Fax: 81-3-5684-7830. E-mail: hiram{at}med.juntendo.ac.jp.

Antimicrobial Agents and Chemotherapy, April 2002, p. 1147-1152, Vol. 46, No. 4
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.4.1147-1152.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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  • Yang, J. A., Park, D. W., Sohn, J. W., Kim, M. J. (2006). Novel PCR-Restriction Fragment Length Polymorphism Analysis for Rapid Typing of Staphylococcal Cassette Chromosome mec Elements. J. Clin. Microbiol. 44: 236-238 [Abstract] [Full Text]  
  • van der Zee, A., Heck, M., Sterks, M., Harpal, A., Spalburg, E., Kazobagora, L., Wannet, W. (2005). Recognition of SCCmec Types According to Typing Pattern Determined by Multienzyme Multiplex PCR-Amplified Fragment Length Polymorphism Analysis of Methicillin-Resistant Staphylococcus aureus. J. Clin. Microbiol. 43: 6042-6047 [Abstract] [Full Text]  
  • Rihn, J. A., Michaels, M. G., Harner, C. D. (2005). Community-Acquired Methicillin-Resistant Staphylococcus aureus: An Emerging Problem in the Athletic Population. Am J Sports Med 33: 1924-1929 [Abstract] [Full Text]  
  • Roesch, A., Linde, H.-J., Landthaler, M., Vogt, T. (2005). Elimination of a Community-Acquired Methicillin-Resistant Staphylococcus aureus Infection in a Nurse With Atopic Dermatitis. Arch Dermatol 141: 1520-1522 [Full Text]  
  • McAleese, F., Murphy, E., Babinchak, T., Singh, G., Said-Salim, B., Kreiswirth, B., Dunman, P., O'Connell, J., Projan, S. J., Bradford, P. A. (2005). Use of Ribotyping To Retrospectively Identify Methicillin-Resistant Staphylococcus aureus Isolates from Phase 3 Clinical Trials for Tigecycline That Are Genotypically Related to Community-Associated Isolates. Antimicrob. Agents Chemother. 49: 4521-4529 [Abstract] [Full Text]  
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  • de Sousa, M. A., Conceicao, T., Simas, C., de Lencastre, H. (2005). Comparison of Genetic Backgrounds of Methicillin-Resistant and -Susceptible Staphylococcus aureus Isolates from Portuguese Hospitals and the Community. J. Clin. Microbiol. 43: 5150-5157 [Abstract] [Full Text]  
  • Qi, W., Ender, M., O'Brien, F., Imhof, A., Ruef, C., McCallum, N., Berger-Bachi, B. (2005). Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus in Zurich, Switzerland (2003): Prevalence of Type IV SCCmec and a New SCCmec Element Associated with Isolates from Intravenous Drug Users. J. Clin. Microbiol. 43: 5164-5170 [Abstract] [Full Text]  
  • Kwon, N. H., Park, K. T., Moon, J. S., Jung, W. K., Kim, S. H., Kim, J. M., Hong, S. K., Koo, H. C., Joo, Y. S., Park, Y. H. (2005). Staphylococcal cassette chromosome mec (SCCmec) characterization and molecular analysis for methicillin-resistant Staphylococcus aureus and novel SCCmec subtype IVg isolated from bovine milk in Korea. J Antimicrob Chemother 56: 624-632 [Abstract] [Full Text]  
  • Berglund, C., Molling, P., Sjoberg, L., Soderquist, B. (2005). Multilocus Sequence Typing of Methicillin-Resistant Staphylococcus aureus from an Area of Low Endemicity by Real-Time PCR. J. Clin. Microbiol. 43: 4448-4454 [Abstract] [Full Text]  
  • Boyle-Vavra, S., Ereshefsky, B., Wang, C.-C., Daum, R. S. (2005). Successful Multiresistant Community-Associated Methicillin-Resistant Staphylococcus aureus Lineage from Taipei, Taiwan, That Carries Either the Novel Staphylococcal Chromosome Cassette mec (SCCmec) Type VT or SCCmec Type IV. J. Clin. Microbiol. 43: 4719-4730 [Abstract] [Full Text]  
  • Kowalski, T. J., Berbari, E. F., Osmon, D. R. (2005). Epidemiology, Treatment, and Prevention of Community-Acquired Methicillin-Resistant Staphylococcus aureus Infections. Mayo Clin Proc. 80: 1201-1208 [Abstract]  
  • Donnio, P.-Y., Oliveira, D. C., Faria, N. A., Wilhelm, N., Le Coustumier, A., de Lencastre, H. (2005). Partial Excision of the Chromosomal Cassette Containing the Methicillin Resistance Determinant Results in Methicillin-Susceptible Staphylococcus aureus. J. Clin. Microbiol. 43: 4191-4193 [Abstract] [Full Text]  
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  • Trindade, P. d. A., Pacheco, R. L., Costa, S. F., Rossi, F., Barone, A. A., Mamizuka, E. M., Levin, A. S. (2005). Prevalence of SCCmec Type IV in Nosocomial Bloodstream Isolates of Methicillin-Resistant Staphylococcus aureus. J. Clin. Microbiol. 43: 3435-3437 [Abstract] [Full Text]  
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  • Giannoudis, P. V., Parker, J., Wilcox, M. H. (2005). Methicillin-resistant Staphylococcus aureus in trauma and orthopaedic practice. J Bone Joint Surg Br 87-B: 749-754 [Full Text]  
  • Shore, A., Rossney, A. S., Keane, C. T., Enright, M. C., Coleman, D. C. (2005). Seven Novel Variants of the Staphylococcal Chromosomal Cassette mec in Methicillin-Resistant Staphylococcus aureus Isolates from Ireland. Antimicrob. Agents Chemother. 49: 2070-2083 [Abstract] [Full Text]  
  • Weese, J. S. (2005). Methicillin-Resistant Staphylococcus aureus: An Emerging Pathogen in Small Animals. Journal of the American Animal Hospital Association 41: 150-157 [Abstract] [Full Text]  
  • Shukla, S. K. (2005). Community-Associated Methicillin-Resistant Staphylococcus aureus and Its Emerging Virulence. Clin Med Res 3: 57-60 [Full Text]  
  • Miller, L. G., Perdreau-Remington, F., Rieg, G., Mehdi, S., Perlroth, J., Bayer, A. S., Tang, A. W., Phung, T. O., Spellberg, B. (2005). Necrotizing Fasciitis Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus in Los Angeles. NEJM 352: 1445-1453 [Abstract] [Full Text]  
  • Juuti, K., Ibrahem, S., Virolainen-Julkunen, A., Vuopio-Varkila, J., Kuusela, P. (2005). The pls Gene Found in Methicillin-Resistant Staphylococcus aureus Strains Is Common in Clinical Isolates of Staphylococcus sciuri. J. Clin. Microbiol. 43: 1415-1419 [Abstract] [Full Text]  
  • (2005). Guidelines for the Management of Adults with Hospital-acquired, Ventilator-associated, and Healthcare-associated Pneumonia. Am. J. Respir. Crit. Care Med. 171: 388-416 [Full Text]  
  • Gomes, A. R., Vinga, S., Zavolan, M., de Lencastre, H. (2005). Analysis of the Genetic Variability of Virulence-Related Loci in Epidemic Clones of Methicillin-Resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 49: 366-379 [Abstract] [Full Text]  
  • Lu, P.-L., Chin, L.-C., Peng, C.-F., Chiang, Y.-H., Chen, T.-P., Ma, L., Siu, L. K (2005). Risk Factors and Molecular Analysis of Community Methicillin-Resistant Staphylococcus aureus Carriage. J. Clin. Microbiol. 43: 132-139 [Abstract] [Full Text]  
  • Ko, K. S., Lee, J.-Y., Suh, J. Y., Oh, W. S., Peck, K. R., Lee, N. Y., Song, J.-H. (2005). Distribution of Major Genotypes among Methicillin-Resistant Staphylococcus aureus Clones in Asian Countries. J. Clin. Microbiol. 43: 421-426 [Abstract] [Full Text]  
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  • Wannet, W. J. B., Spalburg, E., Heck, M. E. O. C., Pluister, G. N., Willems, R. J. L., de Neeling, A. J. (2004). Widespread Dissemination in The Netherlands of the Epidemic Berlin Methicillin-Resistant Staphylococcus aureus Clone with Low-Level Resistance to Oxacillin. J. Clin. Microbiol. 42: 3077-3082 [Abstract] [Full Text]  
  • O'Brien, F. G., Lim, T. T., Chong, F. N., Coombs, G. W., Enright, M. C., Robinson, D. A., Monk, A., Said-Salim, B., Kreiswirth, B. N., Grubb, W. B. (2004). Diversity among Community Isolates of Methicillin-Resistant Staphylococcus aureus in Australia. J. Clin. Microbiol. 42: 3185-3190 [Abstract] [Full Text]  
  • Francois, P., Renzi, G., Pittet, D., Bento, M., Lew, D., Harbarth, S., Vaudaux, P., Schrenzel, J. (2004). A Novel Multiplex Real-Time PCR Assay for Rapid Typing of Major Staphylococcal Cassette Chromosome mec Elements. J. Clin. Microbiol. 42: 3309-3312 [Abstract] [Full Text]  
  • Holden, M. T. G., Feil, E. J., Lindsay, J. A., Peacock, S. J., Day, N. P. J., Enright, M. C., Foster, T. J., Moore, C. E., Hurst, L., Atkin, R., Barron, A., Bason, N., Bentley, S. D., Chillingworth, C., Chillingworth, T., Churcher, C., Clark, L., Corton, C., Cronin, A., Doggett, J., Dowd, L., Feltwell, T., Hance, Z., Harris, B., Hauser, H., Holroyd, S., Jagels, K., James, K. D., Lennard, N., Line, A., Mayes, R., Moule, S., Mungall, K., Ormond, D., Quail, M. A., Rabbinowitsch, E., Rutherford, K., Sanders, M., Sharp, S., Simmonds, M., Stevens, K., Whitehead, S., Barrell, B. G., Spratt, B. G., Parkhill, J. (2004). Complete genomes of two clinical Staphylococcus aureus strains: Evidence for the rapid evolution of virulence and drug resistance. Proc. Natl. Acad. Sci. USA 101: 9786-9791 [Abstract] [Full Text]  
  • Mongkolrattanothai, K., Boyle, S., Murphy, T. V., Daum, R. S. (2004). Novel Non-mecA-Containing Staphylococcal Chromosomal Cassette Composite Island Containing pbp4 and tagF Genes in a Commensal Staphylococcal Species: a Possible Reservoir for Antibiotic Resistance Islands in Staphylococcus aureus. Antimicrob. Agents Chemother. 48: 1823-1836 [Abstract] [Full Text]  
  • Huletsky, A., Giroux, R., Rossbach, V., Gagnon, M., Vaillancourt, M., Bernier, M., Gagnon, F., Truchon, K., Bastien, M., Picard, F. J., van Belkum, A., Ouellette, M., Roy, P. H., Bergeron, M. G. (2004). New Real-Time PCR Assay for Rapid Detection of Methicillin- Resistant Staphylococcus aureus Directly from Specimens Containing a Mixture of Staphylococci. J. Clin. Microbiol. 42: 1875-1884 [Abstract] [Full Text]  
  • Huygens, F., Stephens, A. J., Nimmo, G. R., Giffard, P. M. (2004). mecA Locus Diversity in Methicillin-Resistant Staphylococcus aureus Isolates in Brisbane, Australia, and the Development of a Novel Diagnostic Procedure for the Western Samoan Phage Pattern Clone. J. Clin. Microbiol. 42: 1947-1955 [Abstract] [Full Text]  
  • Diep, B. A., Sensabaugh, G. F., Somboona, N. S., Carleton, H. A., Perdreau-Remington, F. (2004). Widespread Skin and Soft-Tissue Infections Due to Two Methicillin-Resistant Staphylococcus aureus Strains Harboring the Genes for Panton-Valentine Leucocidin. J. Clin. Microbiol. 42: 2080-2084 [Abstract] [Full Text]  
  • Dominguez, T. J. (2004). It's Not a Spider Bite, It's Community-Acquired Methicillin-Resistant Staphylococcus aureus. J Am Board Fam Med 17: 220-226 [Full Text]  
  • Donnio, P.-Y., Preney, L., Gautier-Lerestif, A.-L., Avril, J.-L., Lafforgue, N. (2004). Changes in staphylococcal cassette chromosome type and antibiotic resistance profile in methicillin-resistant Staphylococcus aureus isolates from a French hospital over an 11 year period. J Antimicrob Chemother 53: 808-813 [Abstract] [Full Text]  
  • Hanssen, A.-M., Kjeldsen, G., Sollid, J. U. E. (2004). Local Variants of Staphylococcal Cassette Chromosome mec in Sporadic Methicillin-Resistant Staphylococcus aureus and Methicillin-Resistant Coagulase-Negative Staphylococci: Evidence of Horizontal Gene Transfer?. Antimicrob. Agents Chemother. 48: 285-296 [Abstract] [Full Text]  
  • Robinson, D. A., Enright, M. C. (2003). Evolutionary Models of the Emergence of Methicillin-Resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 47: 3926-3934 [Abstract] [Full Text]  
  • Wisplinghoff, H., Rosato, A. E., Enright, M. C., Noto, M., Craig, W., Archer, G. L. (2003). Related Clones Containing SCCmec Type IV Predominate among Clinically Significant Staphylococcus epidermidis Isolates. Antimicrob. Agents Chemother. 47: 3574-3579 [Abstract] [Full Text]  
  • Ip, M., Lyon, D. J., Chio, F., Enright, M. C., Cheng, A. F. (2003). Characterization of Isolates of Methicillin-Resistant Staphylococcus aureus from Hong Kong by Phage Typing, Pulsed-Field Gel Electrophoresis, and Fluorescent Amplified-Fragment Length Polymorphism Analysis. J. Clin. Microbiol. 41: 4980-4985 [Abstract] [Full Text]  
  • McDougal, L. K., Steward, C. D., Killgore, G. E., Chaitram, J. M., McAllister, S. K., Tenover, F. C. (2003). Pulsed-Field Gel Electrophoresis Typing of Oxacillin-Resistant Staphylococcus aureus Isolates from the United States: Establishing a National Database. J. Clin. Microbiol. 41: 5113-5120 [Abstract] [Full Text]  
  • Aires de Sousa, M., de Lencastre, H. (2003). Evolution of Sporadic Isolates of Methicillin-Resistant Staphylococcus aureus (MRSA) in Hospitals and Their Similarities to Isolates of Community-Acquired MRSA. J. Clin. Microbiol. 41: 3806-3815 [Abstract] [Full Text]  
  • Branger, C., Gardye, C., Galdbart, J.-O., Deschamps, C., Lambert, N. (2003). Genetic Relationship between Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus Strains from France and from International Sources: Delineation of Genomic Groups. J. Clin. Microbiol. 41: 2946-2951 [Abstract] [Full Text]  
  • Katayama, Y., Takeuchi, F., Ito, T., Ma, X. X., Ui-Mizutani, Y., Kobayashi, I., Hiramatsu, K. (2003). Identification in Methicillin-Susceptible Staphylococcus hominis of an Active Primordial Mobile Genetic Element for the Staphylococcal Cassette Chromosome mec of Methicillin-Resistant Staphylococcus aureus. J. Bacteriol. 185: 2711-2722 [Abstract] [Full Text]  
  • Rohrer, S., Berger-Bachi, B. (2003). FemABX Peptidyl Transferases: a Link between Branched-Chain Cell Wall Peptide Formation and {beta}-Lactam Resistance in Gram-Positive Cocci. Antimicrob. Agents Chemother. 47: 837-846 [Full Text]  
  • Zhao, X., Eisner, W., Perl-Rosenthal, N., Kreiswirth, B., Drlica, K. (2003). Mutant Prevention Concentration of Garenoxacin (BMS-284756) for Ciprofloxacin-Susceptible or -Resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 47: 1023-1027 [Abstract] [Full Text]  
  • Boyle-Vavra, S., Yin, S., Challapalli, M., Daum, R. S. (2003). Transcriptional Induction of the Penicillin-Binding Protein 2 Gene in Staphylococcus aureus by Cell Wall-Active Antibiotics Oxacillin and Vancomycin. Antimicrob. Agents Chemother. 47: 1028-1036 [Abstract] [Full Text]  
  • Reipert, A., Ehlert, K., Kast, T., Bierbaum, G. (2003). Morphological and Genetic Differences in Two Isogenic Staphylococcus aureus Strains with Decreased Susceptibilities to Vancomycin. Antimicrob. Agents Chemother. 47: 568-576 [Abstract] [Full Text]  


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