AAC
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kartali, G.
Right arrow Articles by Tsakris, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kartali, G.
Right arrow Articles by Tsakris, A.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, May 2002, p. 1577-1580, Vol. 46, No. 5
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.5.1577-1580.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Outbreak of Infections Caused by Enterobacter cloacae Producing the Integron-Associated ß-Lactamase IBC-1 in a Neonatal Intensive Care Unit of a Greek Hospital

Georgia Kartali,1 Eva Tzelepi,2 Spyros Pournaras,3 Constantina Kontopoulou,1 Fanourios Kontos,3 Danai Sofianou,1 Antonios N. Maniatis,3 and Athanassios Tsakris4*

Department of Microbiology, Hippokration General Hospital,1 Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki,4 Department of Bacteriology, Hellenic Pasteur Institute, Athens,2 Department of Medical Microbiology, University of Thessalia, Larissa, Greece3

Received 22 June 2001/ Returned for modification 23 November 2001/ Accepted 9 February 2002

Nineteen of 27 ceftazidime-resistant Enterobacter cloacae isolates from a neonatal intensive care unit in Thessaloniki, Greece, had genes coding for the novel extended-spectrum ß-lactamase IBC-1; 18 of those 19 harbored similar conjugative plasmids and belonged to two distinct genetic lineages. A synergy test with ceftazidime and imipenem enabled us to identify five unrelated blaIBC-1-carrying E. cloacae isolates from other wards of the hospital. It seems that this integron-associated gene is capable of dispersing both by clonal spread and by gene dissemination.


* Corresponding author. Mailing address: Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54006 Thessaloniki, Greece. Phone: 30 310 99 90 91. Fax: 30 310 99 91 49. E-mail: atsakris{at}med.auth.gr.


Antimicrobial Agents and Chemotherapy, May 2002, p. 1577-1580, Vol. 46, No. 5
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.5.1577-1580.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.




This article has been cited by other articles:




Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Clin. Vaccine Immunol. Clin. Microbiol. Rev.
J. Clin. Microbiol. ALL ASM JOURNALS

Copyright © 2002 by the American Society for Microbiology. All rights reserved.