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Antimicrobial Agents and Chemotherapy, June 2002, p. 1989-1992, Vol. 46, No. 6
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.6.1989-1992.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Determining Linezolid’s Baseline In Vitro Activity in Canada Using Gram-Positive Clinical Isolates Collected prior to Its National Release

James A. Karlowsky,1* Laurie J. Kelly,1 Ian A. Critchley,1 Mark E. Jones,2 Clyde Thornsberry,3 and Daniel F. Sahm1

Focus Technologies, Inc., Herndon, Virginia,1 Focus Technologies, Inc., Hilversum, The Netherlands,2 Focus Technologies, Inc., Franklin, Tennessee3

Received 2 November 2001/ Returned for modification 14 February 2002/ Accepted 12 March 2002

All of the isolates of Staphylococcus aureus (n = 317), Enterococcus species (n = 315), Streptococcus pneumoniae (n = 282), and Staphylococcus epidermidis (n = 176) collected at 16 Canadian microbiology laboratories from October 2000 to April 2001 were susceptible to linezolid. Future studies will determine how linezolid clinical use in Canada affects its in vitro activity.

* Corresponding author. Mailing address: Focus Technologies, Inc., 13665 Dulles Technology Dr., Suite 200, Herndon, VA 20171-4603. Phone: (703) 480-2575. Fax: (703) 480-2670. E-mail: jkarlowsky{at}focusanswers.com.

Antimicrobial Agents and Chemotherapy, June 2002, p. 1989-1992, Vol. 46, No. 6
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.6.1989-1992.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.





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