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Antimicrobial Agents and Chemotherapy, September 2002, p. 3042-3044, Vol. 46, No. 9
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.9.3042-3044.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Surveillance for Antiviral-Agent-Resistant Herpes Simplex Virus in the General Population with Recurrent Herpes Labialis

Teresa H. Bacon,1* Ron J. Boon,1 Margaret Schultz,2 and Cheryl Hodges-Savola3

GlaxoSmithKline Consumer Healthcare, Weybridge, Surrey KT15 0DE, United Kingdom,1 GlaxoSmithKline Pharmaceuticals, Research Triangle Park, North Carolina 27709,2 ViroMed Inc., Minneapolis, Minnesota 553433

Received 26 December 2001/ Returned for modification 29 March 2002/ Accepted 28 May 2002

In a general population survey in the United States, the prevalence of antiviral-agent-resistant herpes simplex virus was very low among more than 1,000 isolates from individuals with an episode of recurrent herpes labialis not treated with topical antiviral agents. Two isolates had borderline resistance to acyclovir (0.2%), and all were susceptible to penciclovir.

* Corresponding author. Mailing address: GlaxoSmithKline Consumer Healthcare, St. George's Ave., Weybridge, Surrey KT15 0DE, United Kingdom. Phone: 44 1932 822185. Fax: 44 1932 822139. E-mail: teresa.h.bacon{at}gsk.com.

Antimicrobial Agents and Chemotherapy, September 2002, p. 3042-3044, Vol. 46, No. 9
0066-4804/02/$04.00+0     DOI: 10.1128/AAC.46.9.3042-3044.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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Copyright © 2002 by the American Society for Microbiology. All rights reserved.