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Antimicrobial Agents and Chemotherapy, January 2003, p. 395-397, Vol. 47, No. 1
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.1.395-397.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Escherichia coli with a Self-Transferable, Multiresistant Plasmid Coding for Metallo-ß-Lactamase VIM-1

Laboratory of Bacteriology, Hellenic Pasteur Institute,¹ Department of Microbiology, Medical School, University of Athens, Athens,³ Laboratory of Microbiology, "Tzanion" General Hospital, Piraeus, Greece²

Received 26 July 2002/ Returned for modification 3 October 2002/ Accepted 25 October 2002

An Escherichia coli strain exhibiting decreased susceptibility to carbapenems was isolated from a hospitalized patient in Greece. The strain carried a self-transferable plasmid coding for metallo-ß-lactamase VIM-1. bla_VIM-1, along with aacA7, dhfrI, and aadA, was included as a gene cassette in a novel class 1 integron. A Citrobacter freundii ampC-derived gene, not associated with the integron, was also located in the same plasmid.

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