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Antimicrobial Agents and Chemotherapy, November 2003, p. 3640-3643, Vol. 47, No. 11
0066-4804/03/$08.00+0 DOI: 10.1128/AAC.47.11.3640-3643.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.
Multiple-Drug Resistance in D-Tartrate-Positive Salmonella enterica Serovar Paratyphi B Isolates from Poultry Is Mediated by Class 2 Integrons Inserted into the Bacterial Chromosome
Angelika Miko, Karin Pries, Andreas Schroeter, and Reiner Helmuth*
National Salmonella Reference Laboratory, Federal Institute for Risk Assessment, D-12277 Berlin, Germany
Received 5 May 2003/
Returned for modification 17 July 2003/
Accepted 25 August 2003
The presence of integrons in 85 multiresistant German isolates of the predominating Salmonella enterica subsp. enterica serovar Paratyphi B dT+ clone was investigated. All isolates possessed a chromosomally located Tn7-like class 2 integron carrying the same dfrA1-sat1-aadA1 array of gene cassettes. Only four isolates (4.7%) revealed an additional class 1 integron with two strains each containing the aadA1 or dfrA1-aadA1 gene cassettes.
* Corresponding author. Mailing address: Federal Institute for Risk Assessment (BfR), Diedersdorfer Weg 1, D-12277 Berlin, Germany. Phone: 49-30-8412-2233. Fax: 49-30-8412-2953. E-mail: r.helmuth{at}bfr.bund.de.
Antimicrobial Agents and Chemotherapy, November 2003, p. 3640-3643, Vol. 47, No. 11
0066-4804/03/$08.00+0 DOI: 10.1128/AAC.47.11.3640-3643.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.
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Copyright © 2003 by the American Society for Microbiology. All rights reserved.