This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Arduino, S. M. Articles by Centrón, D. Search for Related Content PubMed PubMed Citation Articles by Arduino, S. M. Articles by Centrón, D.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, December 2003, p. 3945-3949, Vol. 47, No. 12
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.12.3945-3949.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Molecular Epidemiology of orf513-Bearing Class 1 Integrons in Multiresistant Clinical Isolates from Argentinean Hospitals

Facultad de Medicina de la Universidad de Buenos Aires, (1121) Capital Federal, Argentina,¹ Département de Biochimie, Faculté des Sciences et de Génie, Université Laval, Sainte-Foy, Québec, Canada G1K 7P4,² Centre de Recherche en Infectiologie, Centre de Recherche du CHUL, Sainte-Foy, Québec, Canada G1V 4G2³

Received 12 March 2003/ Returned for modification 23 May 2003/ Accepted 4 September 2003

The spread of orf513-bearing class 1 integrons is associated with bla_CTX-M-2 in gram-negative clinical isolates in Argentina, with In35 being the most frequently found integron (74%). Among 65 isolates without bla_CTX-M-2, only one harbored a novel orf513-bearing class 1 integron with the dfrA3b gene. The finding of orf513 not associated with class 1 integrons in two gram-positive strains indicates the widespread occurrence of this putative site-specific recombinase.

This article has been cited by other articles:

• Quiroga, M. P., Andres, P., Petroni, A., Soler Bistue, A. J. C., Guerriero, L., Vargas, L. J., Zorreguieta, A., Tokumoto, M., Quiroga, C., Tolmasky, M. E., Galas, M., Centron, D. (2007). Complex Class 1 Integrons with Diverse Variable Regions, Including aac(6')-Ib-cr, and a Novel Allele, qnrB10, Associated with ISCR1 in Clinical Enterobacterial Isolates from Argentina. Antimicrob. Agents Chemother. 51: 4466-4470 [Abstract] [Full Text]  
• Toleman, M. A., Bennett, P. M., Walsh, T. R. (2006). Common regions e.g. orf513 and antibiotic resistance: IS91-like elements evolving complex class 1 integrons. J Antimicrob Chemother 58: 1-6 [Abstract] [Full Text]  
• Toleman, M. A., Bennett, P. M., Walsh, T. R. (2006). ISCR Elements: Novel Gene-Capturing Systems of the 21st Century?. Microbiol. Mol. Biol. Rev. 70: 296-316 [Abstract] [Full Text]  
• Soler Bistue, A. J. C., Martin, F. A., Petroni, A., Faccone, D., Galas, M., Tolmasky, M. E., Zorreguieta, A. (2006). Vibrio cholerae InV117, a Class 1 Integron Harboring aac(6')-Ib and blaCTX-M-2, Is Linked to Transposition Genes.. Antimicrob. Agents Chemother. 50: 1903-1907 [Abstract] [Full Text]  
• Valverde, A., Canton, R., Galan, J. C., Nordmann, P., Baquero, F., Coque, T. M. (2006). In117, an Unusual In0-Like Class 1 Integron Containing CR1 and blaCTX-M-2 and Associated with a Tn21-Like Element. Antimicrob. Agents Chemother. 50: 799-802 [Abstract] [Full Text]  
• Valverde, A., Coque, T. M., Sanchez-Moreno, M. P., Rollan, A., Baquero, F., Canton, R. (2004). Dramatic Increase in Prevalence of Fecal Carriage of Extended-Spectrum {beta}-Lactamase-Producing Enterobacteriaceae during Nonoutbreak Situations in Spain. J. Clin. Microbiol. 42: 4769-4775 [Abstract] [Full Text]