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Antimicrobial Agents and Chemotherapy, December 2003, p. 3973-3975, Vol. 47, No. 12
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.12.3973-3975.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Comparative In Vitro Susceptibilities and Bactericidal Activities of Investigational Fluoroquinolone ABT-492 and Other Antimicrobial Agents against Human Mycoplasmas and Ureaplasmas

Ken B. Waites,1,2* Donna M. Crabb,2 and Lynn B. Duffy2

Departments of Pathology,1 Microbiology,University of Alabama at Birmingham, Birmingham, Alabama 352492

Received 30 June 2003/ Returned for modification 10 September 2003/ Accepted 18 September 2003

We determined in vitro susceptibilities for ABT-492 and other antimicrobials against Mycoplasma pneumoniae, Mycoplasma fermentans, Mycoplasma hominis, and Ureaplasma species. ABT-492 MICs were <=1 µg/ml, and the agent was bactericidal against selected isolates of M. pneumoniae and M. hominis. ABT-492 has potential for treatment of infections due to these microorganisms.

* Corresponding author. Mailing address: Department of Pathology WP 230, 619n South 19th St., Birmingham, AL 35249. Phone: (205) 934-4960. Fax: (205) 975-4468. E-mail: waites{at}path.uab.edu.

Antimicrobial Agents and Chemotherapy, December 2003, p. 3973-3975, Vol. 47, No. 12
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.12.3973-3975.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Pereyre, S., Renaudin, H., Bebear, C., Bebear, C. M. (2004). In Vitro Activities of the Newer Quinolones Garenoxacin, Gatifloxacin, and Gemifloxacin against Human Mycoplasmas. Antimicrob. Agents Chemother. 48: 3165-3168 [Abstract] [Full Text]  


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