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Antimicrobial Agents and Chemotherapy, December 2003, p. 3985-3988, Vol. 47, No. 12
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.12.3985-3988.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

In Vitro Susceptibility Testing of Geotrichum capitatum: Comparison of the E-Test, Disk Diffusion, and Sensititre Colorimetric Methods with the NCCLS M27-A2 Broth Microdilution Reference Method

Dipartimento di Biotecnologie Cellulari ed Ematologia, Università "La Sapienza,",¹ Pfizer Italia SpA, Rome,² Servizio di Microbiologia Clinica del Dipartimento di Ematologia ed Oncologia, Ospedale Spirito Santo, Pescara,³ Clinica di Malattie Infettive, Dipartimento di Scienze Mediche e Morfologiche, Università di Udine, Udine, Italy⁴

Received 5 August 2003/ Returned for modification 13 August 2003/ Accepted 8 September 2003

The in vitro activities of amphotericin B, flucytosine, fluconazole, itraconazole, and voriconazole against 23 isolates of Geotrichum capitatum were determined by the National Committee for Clinical Laboratory Standards (NCCLS) M27-A2 microdilution method and the Sensititre and agar diffusion methods. Amphotericin B and voriconazole appeared to be the more active drugs. Sensititre showed the highest rates of agreement with the NCCLS M27-A2 method.

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