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Antimicrobial Agents and Chemotherapy, April 2003, p. 1433-1435, Vol. 47, No. 4
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.4.1433-1435.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Molecular Characterization and Antimicrobial Susceptibility of Fluoroquinolone-Resistant or -Susceptible Streptococcus pneumoniae from Hong Kong

Ian Morrissey,* David J. Farrell, Sarah Bakker, Sylvie Buckridge, and David Felmingham

GR Micro Ltd., London, United Kingdom

Received 19 September 2002/ Returned for modification 8 December 2002/ Accepted 25 January 2003

Fluoroquinolone resistance in Streptococcus pneumoniae isolated from Hong Kong as part of Prospective Resistant Organism Tracking and Epidemiology for the Ketolide Telithromycin 1999/2000 was found to be due to the spread of the Spain23F-1 clone (mainly a Spain23F-1-14 variant). All the isolates were multidrug resistant but were susceptible to quinupristin-dalfopristin, linezolid, and telithromycin. The Spain23F-1 clone also occurred among antimicrobial-susceptible isolates, which suggests that the primary source of this clone may have been Asia rather than Iberia.

* Corresponding author. Mailing address: GR Micro Ltd., 7-9 William Rd., London NW1 3ER, United Kingdom. Phone: 44 (0) 20 7388 7320. Fax: 44 (0) 20 7388 7324. E-mail: i.morrissey{at}grmicro.co.uk.

Antimicrobial Agents and Chemotherapy, April 2003, p. 1433-1435, Vol. 47, No. 4
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.4.1433-1435.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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