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Antimicrobial Agents and Chemotherapy, July 2003, p. 2310-2312, Vol. 47, No. 7
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.7.2310-2312.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Presence of the Tet M Determinant in a Clinical Isolate of Acinetobacter baumannii

Anna Ribera, Joaquim Ruiz, and Jordi Vila*

Servei de Microbiologia, Institut Clinic Infeccions i Immunologia, IDIBAPS, Hospital Clinic, Facultat de Medicina, Universitat de Barcelona, 08036 Barcelona, Spain

Received 2 December 2002/ Returned for modification 10 January 2003/ Accepted 25 March 2003

The tet(M) gene encodes a protein which is related to tetracycline ribosomal protection, one of the mechanisms of tetracycline resistance. A tet(M) gene that is 100% homologous to the tet(M) gene of Staphylococcus aureus has been found in a clinical isolate of Acinetobacter baumannii, which also carries the tet(A) gene encoding a tetracycline efflux pump.

* Corresponding author. Mailing address: Department of Microbiology, Hospital Clinic, Facultat de Medicina, Universitat de Barcelona, Villarroel, 170, 08036 Barcelona, Spain. Phone: 34 93 2275522. Fax: 34 93 2275454. E-mail : vila{at}medicina.ub.es.

Antimicrobial Agents and Chemotherapy, July 2003, p. 2310-2312, Vol. 47, No. 7
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.7.2310-2312.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Peleg, A. Y., Seifert, H., Paterson, D. L. (2008). Acinetobacter baumannii: Emergence of a Successful Pathogen. Clin. Microbiol. Rev. 21: 538-582 [Abstract] [Full Text]  
  • Perez, F., Hujer, A. M., Hujer, K. M., Decker, B. K., Rather, P. N., Bonomo, R. A. (2007). Global Challenge of Multidrug-Resistant Acinetobacter baumannii. Antimicrob. Agents Chemother. 51: 3471-3484 [Full Text]  
  • Agerso, Y., Petersen, A. (2007). The tetracycline resistance determinant Tet 39 and the sulphonamide resistance gene sulII are common among resistant Acinetobacter spp. isolated from integrated fish farms in Thailand. J Antimicrob Chemother 59: 23-27 [Abstract] [Full Text]  
  • Saugar, J. M., Rodriguez-Hernandez, M. J., de la Torre, B. G., Pachon-Ibanez, M. E., Fernandez-Reyes, M., Andreu, D., Pachon, J., Rivas, L. (2006). Activity of Cecropin A-Melittin Hybrid Peptides against Colistin-Resistant Clinical Strains of Acinetobacter baumannii: Molecular Basis for the Differential Mechanisms of Action. Antimicrob. Agents Chemother. 50: 1251-1256 [Abstract] [Full Text]  
  • Agerso, Y., Guardabassi, L. (2005). Identification of Tet 39, a novel class of tetracycline resistance determinant in Acinetobacter spp. of environmental and clinical origin. J Antimicrob Chemother 55: 566-569 [Abstract] [Full Text]  


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