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Antimicrobial Agents and Chemotherapy, July 2003, p. 2339-2341, Vol. 47, No. 7
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.7.2339-2341.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Scopulariopsis brevicaulis, a Fungal Pathogen Resistant to Broad-Spectrum Antifungal Agents

Manuel Cuenca-Estrella,* Alicia Gomez-Lopez, Emilia Mellado, Maria J. Buitrago, Araceli Monzón, and Juan L. Rodriguez-Tudela

Unidad de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain

Received 21 January 2003/ Returned for modification 3 March 2003/ Accepted 15 April 2003

The antifungal susceptibility results for 32 clinical isolates of Scopulariopsis brevicaulis are presented. Flucytosine and itraconazole were inactive in vitro, and MICs of amphotericin B, voriconazole, and terbinafine for all isolates were high, with geometric means of 13, 25.8, and 14.4 µg/ml, respectively.

* Corresponding author. Mailing address: Unidad de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Ctra Majadahonda-Pozuelo Km 2, 28220 Majadahonda, Madrid, Spain. Phone: 34-91-5097961. Fax: 34-91-5097966. E-mail: mcuenca-estrella{at}isciii.es.

Antimicrobial Agents and Chemotherapy, July 2003, p. 2339-2341, Vol. 47, No. 7
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.7.2339-2341.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



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