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Antimicrobial Agents and Chemotherapy, July 2003, p. 2342-2344, Vol. 47, No. 7
0066-4804/03/$08.00+0     DOI: 10.1128/AAC.47.7.2342-2344.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

In Vitro Susceptibilities of Malassezia Species to a New Triazole, Albaconazole (UR-9825), and Other Antifungal Compounds

Department of Microbiology, Hospital Universitario 12 de Octubre, Madrid,¹ Department of Dermatology, Complejo Hospitalario Universitario, Faculty of Medicine, Santiago de Compostela, Spain²

Received 26 December 2002/ Returned for modification 12 March 2003/ Accepted 17 April 2003

The in vitro activity of the new triazole albaconazole (UR-9825) in comparison with those of flucytosine, fluconazole, ketoconazole, itraconazole, and voriconazole against 70 strains of Malassezia spp. was determined by a microdilution method using a colorimetric indicator for metabolic activity. Albaconazole showed an in vitro profile similar to those of the different antifungals tested (MIC 0.06 µg/ml for all the strains).

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