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Antimicrobial Agents and Chemotherapy, January 2004, p. 329-332, Vol. 48, No. 1
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.1.329-332.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

blaVIM-7, an Evolutionarily Distinct Metallo-ß-Lactamase Gene in a Pseudomonas aeruginosa Isolate from the United States

Mark A. Toleman,1* Kenneth Rolston,2 Ronald N. Jones,3,4 and Timothy R. Walsh1

Department of Pathology and Microbiology, University of Bristol, Bristol BS8 1TD, United Kingdom,1 Anderson Medical Center, Houston, Texas,2 The JONES Group/JMI Laboratories, North Liberty, Iowa,3 Tufts University School of Medicine, Boston, Massachusetts4

Received 20 March 2003/ Returned for modification 28 April 2003/ Accepted 18 August 2003

As part of the CANCER Antimicrobial Surveillance Program in North America, a Pseudomonas aeruginosa isolate, strain 07-406, was shown to possess a metallo-ß-lactamase, designated VIM-7. blaVIM-7 is located on a 24-kb plasmid which can be readily transferred into Enterobacteriaceae and other pseudomonads. This is the first report of a mobile metallo-ß-lactamase gene, blaVIM-7, being detected within the United States.


* Corresponding author. Mailing address: Department of Pathology and Microbiology, University of Bristol, Bristol BS8 1TD, United Kingdom. Phone: 44 117 9287522. Fax 44 117 9287896. E-mail: Mark.Toleman{at}bristol.ac.uk.


Antimicrobial Agents and Chemotherapy, January 2004, p. 329-332, Vol. 48, No. 1
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.1.329-332.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.




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