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Antimicrobial Agents and Chemotherapy, November 2004, p. 4488-4490, Vol. 48, No. 11
0066-4804/04/$08.00+0 DOI: 10.1128/AAC.48.11.4488-4490.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.
School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot,1 Israel Institute for Biological Research, Ness Ziona, Israel,3 Department of Clinical Veterinary Science, University of Bristol, Langford, Somerset, United Kingdom2
Received 17 March 2004/ Returned for modification 15 June 2004/ Accepted 26 July 2004
This report presents evidence that dogs recover from acute canine monocytic ehrlichiosis (CME) after 16 days of doxycycline treatment (10 mg/kg of body weight every 24 h). Blood PCR was as valuable as splenic aspirate PCR for early diagnosis of acute CME. Splenic aspirate PCR was, however, superior to blood PCR for the evaluation of ehrlichial elimination.
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