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Antimicrobial Agents and Chemotherapy, December 2004, p. 4915-4918, Vol. 48, No. 12
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.12.4915-4918.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Members of the Genera Paenibacillus and Rhodococcus Harbor Genes Homologous to Enterococcal Glycopeptide Resistance Genes vanA and vanB

Department of Veterinary Pathobiology, The Royal Veterinary and Agricultural University, Frederiksberg,¹ Danish Institute for Food and Veterinary Research, Copenhagen, Denmark²

Received 6 July 2004/ Returned for modification 16 August 2004/ Accepted 19 August 2004

Genes homologous to enterococcal glycopeptide resistance genes vanA and vanB were found in glycopeptide-resistant Paenibacillus and Rhodococcus strains from soil. The putative D-Ala:D-Lac ligase genes in Paenibacillus thiaminolyticus PT-2B1 and Paenibacillus apiarius PA-B2B were closely related to vanA (92 and 87%) and flanked by genes homologous to vanH and vanX in vanA operons.

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