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Antimicrobial Agents and Chemotherapy, February 2004, p. 602-604, Vol. 48, No. 2
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.2.602-604.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

In Vitro Activities of New Antimicrobials against Nocardia brasiliensis

Lucio Vera-Cabrera,1* Eva Gonzalez,1 Sung H. Choi,2 and Oliverio Welsh1

Laboratorio Interdisciplinario de Investigación Dermatológica, Servicio de Dermatología, Hospital Universitario, Monterrey, Nuevo León, México,1 Research Lab., Dong-A Pharm. Co., Ltd., Yongin, Korea2

Received 16 April 2003/ Returned for modification 19 July 2003/ Accepted 4 October 2003

The in vitro sensitivities of 30 strains of Nocardia brasiliensis to DA-7867, gatifloxacin, moxifloxacin, and BMS-284756 (garenoxacin) were determined using the broth microdilution method. All N. brasiliensis strains were sensitive to these antimicrobials. The most active drug in vitro was DA-7867, with a MIC at which 90% of the isolates tested were inhibited of 0.03 µg/ml and a MIC at which 50% of the isolates tested were inhibited of 0.06 µg/ml.

* Corresponding author. Mailing address: Servicio de Dermatología, Hospital Universitario, U.A.N.L., Madero y Gonzalitos, Colonia Mitras Centro, C.P. 64460, Monterrey, N.L., México. Phone: 5281 8348 0383. Fax: 5281 8348 44 07. E-mail: luvera_99{at}yahoo.com.

Antimicrobial Agents and Chemotherapy, February 2004, p. 602-604, Vol. 48, No. 2
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.2.602-604.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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