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Antimicrobial Agents and Chemotherapy, February 2004, p. 623-625, Vol. 48, No. 2
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.2.623-625.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Intact mutS in Laboratory-Derived and Clinical Glycopeptide-Intermediate Staphylococcus aureus Strains

Arunachalam Muthaiyan, Radheshyam K. Jayaswal, and Brian J. Wilkinson*

Microbiology Group, Department of Biological Sciences, Illinois State University, Normal, Illinois 61790-4120

Received 24 June 2003/ Returned for modification 7 September 2003/ Accepted 2 November 2003

The mutS gene of the methyl-directed mismatch repair system was sequenced in 10 parent and glycopeptide-intermediate Staphylococcus aureus strains. The mutS gene was intact in all strains studied. Hence, mutations in this gene had played no role in the development of vancomycin resistance in these strains.

* Corresponding author. Mailing address: Department of Biological Sciences, Illinois State University, Normal, IL 61790-4120. Phone: (309) 438-7244. Fax: (309) 438-3722. E-mail: bjwilkin{at}ilstu.edu.

Antimicrobial Agents and Chemotherapy, February 2004, p. 623-625, Vol. 48, No. 2
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.2.623-625.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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