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Antimicrobial Agents and Chemotherapy, February 2004, p. 629-631, Vol. 48, No. 2
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.2.629-631.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

CTX-M-12 ß-Lactamase in a Klebsiella pneumoniae Clinical Isolate in Colombia

Maria Virginia Villegas,¹ Adriana Correa,¹ Federico Perez,¹ Tania Zuluaga,¹ Marcela Radice,² Gabriel Gutkind,² José María Casellas,³ Juan Ayala,⁴ Karen Lolans,⁵ John P. Quinn,^5* and the Colombian Nosocomial Resistance Study Group^1,

Línea de Resistencia Bacteriana, Centro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia,¹ Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 954, 1113 Buenos Aires,² División Microbiología Clínica, Centro de Investigaciones Biológicas y Clínicas (CIBIC), Rosario, Argentina,³ Centro de Biología Molecular "Severo Ochoa" (CSIC), Universidad Autónoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain,⁴ Division of Infectious Diseases, Rush Medical School, Cook County Hospital, Chicago, Illinois 60612⁵

Received 27 June 2003/ Returned for modification 23 October 2003/ Accepted 6 November 2003

We describe the detection of the CTX-M-12 ß-lactamase from a clinical isolate of Klebsiella pneumoniae in Colombia. Screening of nosocomial Klebsiella spp. and Escherichia coli isolates from a network of teaching hospitals revealed the presence of CTX-M enzymes in multiple cities. This is the first description of CTX-M in Colombia.

Contributing members of the Colombian Nosocomial Resistance Study Group are listed in the Acknowledgments.

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