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Antimicrobial Agents and Chemotherapy, February 2004, p. 629-631, Vol. 48, No. 2
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.2.629-631.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

CTX-M-12 ß-Lactamase in a Klebsiella pneumoniae Clinical Isolate in Colombia

Maria Virginia Villegas,1 Adriana Correa,1 Federico Perez,1 Tania Zuluaga,1 Marcela Radice,2 Gabriel Gutkind,2 José María Casellas,3 Juan Ayala,4 Karen Lolans,5 John P. Quinn,5* and the Colombian Nosocomial Resistance Study Group1,{dagger}

Línea de Resistencia Bacteriana, Centro Internacional de Entrenamiento e Investigaciones Médicas (CIDEIM), Cali, Colombia,1 Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 954, 1113 Buenos Aires,2 División Microbiología Clínica, Centro de Investigaciones Biológicas y Clínicas (CIBIC), Rosario, Argentina,3 Centro de Biología Molecular "Severo Ochoa" (CSIC), Universidad Autónoma de Madrid, Campus de Cantoblanco, 28049 Madrid, Spain,4 Division of Infectious Diseases, Rush Medical School, Cook County Hospital, Chicago, Illinois 606125

Received 27 June 2003/ Returned for modification 23 October 2003/ Accepted 6 November 2003

We describe the detection of the CTX-M-12 ß-lactamase from a clinical isolate of Klebsiella pneumoniae in Colombia. Screening of nosocomial Klebsiella spp. and Escherichia coli isolates from a network of teaching hospitals revealed the presence of CTX-M enzymes in multiple cities. This is the first description of CTX-M in Colombia.

* Corresponding author. Mailing address: Division of Infectious Diseases, Rush Medical School, Cook County Hospital, 1900 W Polk, Rm. 1258, Chicago, IL 60612. Phone: (312) 633-7955. E-mail: john_p_quinn{at}rush.edu.

{dagger} Contributing members of the Colombian Nosocomial Resistance Study Group are listed in the Acknowledgments.

Antimicrobial Agents and Chemotherapy, February 2004, p. 629-631, Vol. 48, No. 2
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.2.629-631.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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