This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Reinert, R. R.
Right arrow Articles by Al-Lahham, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Reinert, R. R.
Right arrow Articles by Al-Lahham, A.
Right arrowPubmed/NCBI databases
*Compound via MeSH
*Substance via MeSH
Medline Plus Health Information
*Antibiotics
Hazardous Substances DB
*ERYTHROMYCIN

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, April 2004, p. 1369-1373, Vol. 48, No. 4
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.4.1369-1373.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Clonal Relatedness of Erythromycin-Resistant Streptococcus pyogenes Isolates in Germany

Ralf R. Reinert,1* Rudolf Lütticken,1 Joyce A. Sutcliffe,2 Amelia Tait-Kamradt,3 Murat Y. Cil,1 Holger M. Schorn,1 André Bryskier,4 and Adnan Al-Lahham1

Institute for Medical Microbiology, National Reference Center for Streptococci, University Hospital, D-52057 Aachen, Germany,1 Rib-X Pharmaceuticals, New Haven,2 Pfizer Central Research and Development, Groton, Connecticut,3 Aventis Pharma, Hoechst Marion Roussel, Romainville, France4

Received 25 July 2003/ Returned for modification 8 November 2003/ Accepted 6 January 2004

In a nationwide study in Germany, a total of 381 Streptococcus pyogenes were collected. Erythromycin A-resistant strains were characterized for the underlying resistance genotype, showing 55.6% had the efflux type mef(A), 31.5% had erm(A), and 13.0% had erm(B). A total of 23 different multilocus sequence types were observed.

* Corresponding author. Mailing address: Institute for Medical Microbiology, National Reference Center for Streptococci, University Hospital, Pauwelsstrasse 30, D-52057 Aachen, Germany. Phone: 49 241 8089787. Fax: 49 241 8082483. E-mail: Reinert{at}rwth-aachen.de.

Antimicrobial Agents and Chemotherapy, April 2004, p. 1369-1373, Vol. 48, No. 4
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.4.1369-1373.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Richter, S. S., Heilmann, K. P., Dohrn, C. L., Beekmann, S. E., Riahi, F., Garcia-de-Lomas, J., Ferech, M., Goossens, H., Doern, G. V. (2008). Increasing telithromycin resistance among Streptococcus pyogenes in Europe. J Antimicrob Chemother 61: 603-611 [Abstract] [Full Text]  
  • Palmieri, C., Vecchi, M., Littauer, P., Sundsfjord, A., Varaldo, P. E., Facinelli, B. (2006). Clonal Spread of Macrolide- and Tetracycline-Resistant [erm(A) tet(O)] emm77 Streptococcus pyogenes Isolates in Italy and Norway. Antimicrob. Agents Chemother. 50: 4229-4230 [Full Text]  
  • Robinson, D. A., Sutcliffe, J. A., Tewodros, W., Manoharan, A., Bessen, D. E. (2006). Evolution and global dissemination of macrolide-resistant group a streptococci.. Antimicrob. Agents Chemother. 50: 2903-2911 [Abstract] [Full Text]  
  • Littauer, P., Caugant, D. A., Sangvik, M., Hoiby, E. A., Sundsfjord, A., Simonsen, G. S., the Norwegian Macrolide Study Group, (2006). Macrolide-Resistant Streptococcus pyogenes in Norway: Population Structure and Resistance Determinants.. Antimicrob. Agents Chemother. 50: 1896-1899 [Abstract] [Full Text]  
  • McGregor, K. F., Spratt, B. G. (2005). Identity and Prevalence of Multilocus Sequence Typing-Defined Clones of Group A Streptococci within a Hospital Setting. J. Clin. Microbiol. 43: 1963-1967 [Abstract] [Full Text]  
  • Doktor, S. Z., Beyer, J. M., Flamm, R. K., Shortridge, V. D. (2005). Comparison of emm Typing and Ribotyping with Three Restriction Enzymes To Characterize Clinical Isolates of Streptococcus pyogenes. J. Clin. Microbiol. 43: 150-155 [Abstract] [Full Text]  
  • Szczypa, K., Sadowy, E., Izdebski, R., Hryniewicz, W. (2004). A rapid increase in macrolide resistance in Streptococcus pyogenes isolated in Poland during 1996-2002. J Antimicrob Chemother 54: 828-831 [Abstract] [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»