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Antimicrobial Agents and Chemotherapy, April 2004, p. 1430-1432, Vol. 48, No. 4
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.4.1430-1432.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Antimicrobial Susceptibility and Mechanisms of Resistance to Quinolones and ß-Lactams in Acinetobacter Genospecies 3

A. Ribera,1 F. Fernández-Cuenca,2 A. Beceiro,3 G. Bou,3 L. Martínez-Martínez,2 A. Pascual,2 J. M. Cisneros,4 J. Rodríguez-Baño,5 J. Pachón,4 J. Vila,1* the Spanish Group for Nosocomial Infection (GEIH),{dagger}

Servei de Microbiologia, Institut Clínic Infeccions i Immunologia, IDIBAPS, Hospital Clínic, 08036 Barcelona,1 Servicios de Microbiología y de,2 Enfermedades Infecciosas, Hospital Virgen de la Macarena, 41071 Seville,5 Servicio de Enfermedades Infecciosas, Hospital Universitario Virgen del Rocio, 41013 Seville,4 Servicio de Microbiología, Hospital Juan Canalejo, La Coruña, Spain3

Received 1 July 2003/ Returned for modification 26 September 2003/ Accepted 17 December 2003

Antimicrobial susceptibility was determined in 15 epidemiologically unrelated clinical isolates of Acinetobacter genospecies 3. Moreover, the mechanisms of resistance to some ß-lactam antibiotics may be associated with the presence of a chromosomal cephalosporinase, AmpC, and the resistance to quinolones related to mutations in the gyrA and parC genes.

* Corresponding author. Mailing address: Department of Microbiology, Hospital Clinic, Facultat de Medicina, Universitat de Barcelona, Villarroel 170, 08036 Barcelona, Spain. Phone: 34.93.2275522. Fax: 34.93.2275454. E-mail: vila{at}medicina.ub.es.

{dagger} Contributing members of the Spanish Group for Nosocomial Infection are listed in Acknowledgments.

Antimicrobial Agents and Chemotherapy, April 2004, p. 1430-1432, Vol. 48, No. 4
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.4.1430-1432.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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