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Antimicrobial Agents and Chemotherapy, June 2004, p. 2277-2279, Vol. 48, No. 6
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.6.2277-2279.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Nosocomial Outbreak of Extended-Spectrum ß-Lactamase SHV-5-Producing Isolates of Pseudomonas aeruginosa in Athens, Greece

Laurent Poirel,1 Evangelia Lebessi,2 Marisa Castro,1 Cindy Fèvre,1 Maria Foustoukou,2 and Patrice Nordmann1*

Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, 94275 Le Kremlin-Bicêtre, France,1 Department of Clinical Microbiology, P. and A. Kyriakou Children's Hospital, Athens, Greece2

Received 22 August 2003/ Returned for modification 16 November 2003/ Accepted 21 February 2004

Seven nonrepetitive Pseudomonas aeruginosa isolates producing the clavulanic acid-inhibited extended-spectrum ß-lactamase SHV-5 were isolated in the same hospital in Athens, Greece, from 1998 to 2002. All isolates except one were clonally related, and the blaSHV-5 gene was chromosomally located. This study underlined that this gene, which is widespread in Enterobacteriaceae in Greece, may disseminate also in P. aeruginosa.

* Corresponding author. Mailing address: Service de Bactériologie-Virologie, Hôpital de Bicêtre, 78 rue du Général Leclerc, 94275 Le Kremlin-Bicêtre cedex, France. Phone: 33-1-45-21-36-32. Fax: 33-1-45-21-63-40. E-mail: nordmann.patrice{at}bct.ap-hop-paris.fr.

Antimicrobial Agents and Chemotherapy, June 2004, p. 2277-2279, Vol. 48, No. 6
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.6.2277-2279.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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