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Antimicrobial Agents and Chemotherapy, July 2004, p. 2716-2718, Vol. 48, No. 7
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.7.2716-2718.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Antimicrobial Susceptibility Patterns and Macrolide Resistance Genes of ß-Hemolytic Streptococci in Korea

Young Uh,1* In Ho Jang,1 Gyu Yel Hwang,1 Mi Kyung Lee,1 Kap Jun Yoon,1 and Hyo Youl Kim2

Departments of Laboratory Medicine,1 Infectious Disease, Yonsei University Wonju College of Medicine, Wonju, South Korea2

Received 28 December 2003/ Returned for modification 29 January 2004/ Accepted 29 February 2004

In 540 beta-hemolytic streptococci, the rates of resistance to tetracycline, chloramphenicol, erythromycin, and clindamycin were 80.0, 22.8, 20.2, and 19.1%, respectively. Of the erythromycin-resistant isolates, 63.3% had the constitutive macrolide-lincosamide-streptogramin B (MLSB) resistance phenotype, 23.9% had the M phenotype, and 12.8% had the inducible MLSB resistance phenotype. The constitutive MLSB resistance phenotype with the erm(B) gene was dominant in Korea.

* Corresponding author. Mailing address: Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Ilsan-dong 162, Wonju, Kangwon-do, South Korea. Phone: 82-33-741-1592. Fax: 82-33-731-0506. E-mail: u931018{at}wonju.yonsei.ac.kr.

Antimicrobial Agents and Chemotherapy, July 2004, p. 2716-2718, Vol. 48, No. 7
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.7.2716-2718.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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