This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Reprints and Permissions Copyright Information Books from ASM Press MicrobeWorld Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Ortoneda, M. Articles by Guarro, J. Search for Related Content PubMed PubMed Citation Articles by Ortoneda, M. Articles by Guarro, J.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, July 2004, p. 2727-2729, Vol. 48, No. 7
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.7.2727-2729.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

In Vitro Interactions of Approved and Novel Drugs against Paecilomyces spp.

Unitat de Microbiologia, Facultat de Medicina,¹ Laboratori de Microbiologia, Hospital Universitari de Sant Joan de Reus, Universitat Rovira i Virgili, Reus, Spain²

Received 19 February 2004/ Returned for modification 21 February 2004/ Accepted 27 February 2004

We have evaluated the in vitro activity of 15 combinations of antifungal drugs (amphotericin B, itraconazole, voriconazole, albaconazole, ravuconazole, terbinafine, and micafungin) against four isolates of Paecilomyces variotii and three of P. lilacinus. The interaction of terbinafine with the four azoles was synergistic for 53% of the combinations, while the interactions of both amphotericin B and micafungin with the rest of antifungal agents were mainly indifferent.

This article has been cited by other articles:

• Chang, B. P.-H., Sun, P.-L., Huang, F.-Y., Tsai, T.-C., Lin, C.-C., Lee, M.-D., Chen, Y.-C., Sheu, J.-C., Tsai, J.-D. (2008). Paecilomyces lilacinus peritonitis complicating peritoneal dialysis cured by oral voriconazole and terbinafine combination therapy. J Med Microbiol 57: 1581-1584 [Abstract] [Full Text]  
• Pasqualotto, A. C., Denning, D. W. (2008). New and emerging treatments for fungal infections. J Antimicrob Chemother 61: i19-i30 [Abstract] [Full Text]  
• Serena, C., Fernandez-Torres, B., Pastor, F. J., Trilles, L., Lazera, M. d. S., Nolard, N., Guarro, J. (2005). In Vitro Interactions of Micafungin with Other Antifungal Drugs against Clinical Isolates of Four Species of Cryptococcus. Antimicrob. Agents Chemother. 49: 2994-2996 [Abstract] [Full Text]