This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Achour, W.
Right arrow Articles by Ben Hassen, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Achour, W.
Right arrow Articles by Ben Hassen, A.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, July 2004, p. 2757-2759, Vol. 48, No. 7
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.7.2757-2759.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

rpoB Mutations in Streptococcus mitis Clinical Isolates Resistant to Rifampin

Wafa Achour,1 Olfa Guenni,1 Marguerite Fines,2 Roland Leclercq,2* and Assia Ben Hassen1

Laboratoire du Centre National de Greffe de Moelle Osseuse, 1006 Tunis, Tunisia,1 Service de Microbiologie, CHU Côte de Nacre, 14003 Caen, France2

Received 4 September 2003/ Returned for modification 22 November 2003/ Accepted 3 March 2004

Activity of rifampin against 129 Streptococcus mitis isolates obtained from patients with hematologic cancer was investigated. One hundred twenty-five strains were susceptible to rifampin, and 4 were resistant (MIC = 32 to 64 µg/ml). Resistance to rifampin was related to mutations in the rpoB gene: His526Asn in three strains and His526Asp in one strain.

* Corresponding author. Mailing address: CHU de Caen, Service de Microbiologie, Ave. Côte de Nacre, 14033 Caen Cedex, France. Phone: (33) 02 31 06 45 72. Fax: (33) 02 31 06 45 73. E-mail: leclercq-r{at}chu-caen.fr

Antimicrobial Agents and Chemotherapy, July 2004, p. 2757-2759, Vol. 48, No. 7
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.7.2757-2759.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

  • Mullin, S., Rothstein, D. M., Murphy, C. K. (2006). Activity of Novel Benzoxazinorifamycins against Rifamycin-Resistant Streptococcus pyogenes.. Antimicrob. Agents Chemother. 50: 1908-1909 [Full Text]  


Copyright © 2009 by the American Society for Microbiology.   For an alternate route to Journals.ASM.org, visit: http://intl-journals.asm.org | More Info»