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Antimicrobial Agents and Chemotherapy, September 2004, p. 3591-3593, Vol. 48, No. 9
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.9.3591-3593.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Combination Therapy Using Sodium Antimony Gluconate in Stearylamine-Bearing Liposomes against Established and Chronic Leishmania donovani Infection in BALB/c Mice

Swati Pal, Rajesh Ravindran, and Nahid Ali*

Infectious Diseases Group, Indian Institute of Chemical Biology, Calcutta, India

Received 29 March 2004/ Returned for modification 12 May 2004/ Accepted 26 May 2004

In this work we report the activity seen with combination therapy using sodium antimony gluconate in liposomes composed of egg phosphatidyl choline and stearylamine for elimination of Leishmania donovani parasites from the liver and spleen of BALB/c mice with established and chronic infections.

* Corresponding author. Mailing address: Indian Institute of Chemical Biology, 4 Raja S.C. Mullick Rd., Calcutta 700032, India. Phone: 009133 24733491. Fax: 009133 24735197. E-mail: nali{at}iicb.res.in.

Antimicrobial Agents and Chemotherapy, September 2004, p. 3591-3593, Vol. 48, No. 9
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.9.3591-3593.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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