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Antimicrobial Agents and Chemotherapy, September 2004, p. 3598-3601, Vol. 48, No. 9
0066-4804/04/$08.00+0     DOI: 10.1128/AAC.48.9.3598-3601.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Drug Susceptibility and Genetic Evaluation of Plasmodium falciparum Isolates Obtained in Four Distinct Geographical Regions of Kenya

Abigael Mbaisi, Pamela Liyala, Fredrick Eyase, Rachel Achilla, Hosea Akala, Julia Wangui, Josphat Mwangi, Finnley Osuna, Uzma Alam, Bonnie L. Smoak, Jon M. Davis, Dennis E. Kyle, Rodney L. Coldren, Carl Mason, and Norman C. Waters^*

U.S. Army Medical Research Unit, Nairobi, Kenya

Received 23 January 2004/ Returned for modification 5 March 2004/ Accepted 8 May 2004

The drug resistance profiles of Plasmodium falciparum isolated from four regions in Kenya were analyzed for drug resistance profiles. We observed variability in resistance to a broad range of antimalarial drugs across Kenya as determined from in vitro drug susceptibility screening and genotyping analysis.

Present address: Division of Preventive Medicine, Walter Reed Army Institute of Research, Silver Spring, Md.

Present address: Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.

Present address: Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.

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