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Antimicrobial Agents and Chemotherapy, January 2005, p. 441-443, Vol. 49, No. 1
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.1.441-443.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Emergence of CTX-M-15-Producing Enterobacteria in Cameroon and Characterization of a blaCTX-M-15-Carrying Element

J. Gangoue-Pieboji,1,2 V. Miriagou,1* S. Vourli,1 E. Tzelepi,1 P. Ngassam,2 and L. S. Tzouvelekis1,3

Laboratory of Bacteriology, Hellenic Pasteur Institute,1 Department of Microbiology, Medical School, University of Athens, Athens, Greece,3 Laboratory of General Biology, Faculty of Sciences, University of Yaounde I, Yaounde, Cameroon2

Received 23 April 2004/ Returned for modification 17 July 2004/ Accepted 18 September 2004

CTX-M-15-producing Klebsiella pneumoniae and Escherichia coli emerged recently in Cameroon. CTX-M-15 was encoded by two different multiresistance plasmids, of which one carried an ISEcp1-blaCTX-M-15 element flanked by a 5-bp target site duplication and inserted within a Tn2-derived sequence. A truncated form of this element in the second plasmid was identified.


* Corresponding author. Mailing address: Laboratory of Bacteriology, Hellenic Pasteur Institute, Vas. Sofias 127, Athens 11521, Greece. Phone: 30 210 6478810. Fax: 30 210 6423498. E-mail: miriagou{at}mail.pasteur.gr.


Antimicrobial Agents and Chemotherapy, January 2005, p. 441-443, Vol. 49, No. 1
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.1.441-443.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.




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