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Antimicrobial Agents and Chemotherapy, October 2005, p. 4404-4405, Vol. 49, No. 10
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.10.4404-4405.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Low Rates of Cutaneous Adverse Reactions to Alcohol-Based Hand Hygiene Solution during Prolonged Use in a Large Teaching Hospital

M. Graham,1 R. Nixon,2 L. J. Burrell,1 C. Bolger,1 P. D. R. Johnson,1,3 and M. L. Grayson1,3,4*

Infectious Diseases Department, Austin Health, Heidelberg, 3084,1 Occupational Dermatology Service, Skin and Cancer Foundation Inc., Carlton South, 3053,2 Department of Medicine, University of Melbourne,3 Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia4

Received 27 February 2005/ Returned for modification 9 May 2005/ Accepted 8 July 2005

We assessed cutaneous adverse reactions (CARs) to alcohol-based hand rub (ABHR) after the introduction of a hand hygiene culture change program at our institution. CARs were infrequent among exposed health care workers (HCWs) (13/2,750; 0.47%; 1 CAR per 72 years of HCW exposure) and were not influenced by the duration or intensity of ABHR use but were associated with the presence of irritant contact dermatitis.

* Corresponding author. Mailing address: Infectious Diseases Department, Austin Hospital, Austin Health, Studley Rd., Heidelberg, VIC, Australia 3084. Phone: (613) 9496 6676. Fax: (613) 9496 6677. E-mail: lindsay.grayson{at}austin.org.au.

Antimicrobial Agents and Chemotherapy, October 2005, p. 4404-4405, Vol. 49, No. 10
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.10.4404-4405.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



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