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Antimicrobial Agents and Chemotherapy, November 2005, p. 4784-4786, Vol. 49, No. 11
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.11.4784-4786.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

High Prevalence of Glycopeptide Resistance Genes vanB, vanD, and vanG Not Associated with Enterococci in Human Fecal Flora

M.-C. Domingo,1,2 A. Huletsky,1,2 R. Giroux,1 K. Boissinot,1,2 F. J. Picard,1,2 P. Lebel,3 M. J. Ferraro,4 and M. G. Bergeron1,2*

Centre de Recherche en Infectiologie de l'Université Laval, CHUQ, Pavillon CHUL,1 Division de Microbiologie, Faculté de Médecine, Université Laval, Sainte-Foy,2 Département de Microbiologie, Hôpital Général de Montréal, McGill University Health Center, Montréal, Québec, Canada,3 Department of Clinical Microbiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts4

Received 4 May 2005/ Returned for modification 26 June 2005/ Accepted 23 July 2005

The presence of Enterococcus-associated vancomycin resistance genes vanA, vanB, vanD, vanE, and vanG in rectal swabs was investigated in two hospitals using PCR. All vanA genes detected were associated with vancomycin-resistant enterococci (VRE), whereas VRE-associated vanB genes were detected in only one hospital (4.7%). However, in both hospitals, high prevalences of vanB (6.2 and 2.3%), vanD (43.8 and 26.7%), and vanG (10.5 and 6.9%) genes not associated with enterococci were found.


* Corresponding author. Mailing address: Centre de Recherche en Infectiologie de l'Université Laval, CHUQ (Pavillon CHUL), 2705 boul. Laurier, Sainte-Foy, Québec, G1V 4G2, Canada. Phone: (418) 654-2705. Fax: (418) 654-2715. E-mail: michel.g.bergeron{at}crchul.ulaval.ca.


Antimicrobial Agents and Chemotherapy, November 2005, p. 4784-4786, Vol. 49, No. 11
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.11.4784-4786.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.




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