AAC
Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrowReprints and Permissions
Right arrow Copyright Information
Right arrow Books from ASM Press
Right arrow MicrobeWorld
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wills, Q. F.
Right arrow Articles by Soothill, J. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wills, Q. F.
Right arrow Articles by Soothill, J. S.

 Previous Article  |  Next Article 

Antimicrobial Agents and Chemotherapy, March 2005, p. 1220-1221, Vol. 49, No. 3
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.3.1220-1221.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Experimental Bacteriophage Protection against Staphylococcus aureus Abscesses in a Rabbit Model

Quintin F. Wills,1 Claire Kerrigan,1 and James S. Soothill1*

Infectious Diseases and Microbiology Unit, Institute of Child Health, University College London, London, United Kingdom1

Received 29 June 2004/ Returned for modification 28 August 2004/ Accepted 11 November 2004

In a rabbit model of wound infection caused by Staphylococcus aureus, 2 x 109 PFU of staphylococcal phage prevented abscess formation in rabbits when it was injected simultaneously with S. aureus (8 x 107 CFU) into the same subcutaneous site. Phage multiplied in the tissues. Phages might be a valuable prophylaxis against staphylococcal infection.

* Corresponding author. Mailing address: Dept. of Microbiology, CB Labs-Level 4, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, United Kingdom. Phone: 44 207 405 9200, ext. 5237. Fax: 44 207 905 2736. E-mail: soothj{at}gosh.nhs.uk.

Antimicrobial Agents and Chemotherapy, March 2005, p. 1220-1221, Vol. 49, No. 3
0066-4804/05/$08.00+0     doi:10.1128/AAC.49.3.1220-1221.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:



Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Clin. Vaccine Immunol. Clin. Microbiol. Rev.
J. Clin. Microbiol. ALL ASM JOURNALS

Copyright © 2005 by the American Society for Microbiology. All rights reserved.